Results 101 to 110 of about 2,947,586 (291)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A population model of two-strains tumors with piecewise constant arguments

open access: yesKuwait Journal of Science, 2015
In this study, the population growth of the brain tumor GBM, is constructed such as( )( ( ) ( [ ] )) ( ) ( [ ] ) ( ) ( [ ] )( )( ( ) ( [ ] )) ( [ ] ) ( ) [ ]1 1 1 2 1 12 2 1 2 1 2d = ( ) rx t R x t x t x t y t d x t x tdd =r y t R y t y t x t y t d y( ) (
FATMA BOZKURT, İLHAN OZTURK
doaj  

Predator-prey Activity-Tuned Ecological System: An Exhilarating Rollercoaster of Survival [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences
In natural ecosystems, the timing of daily activity in predator and prey plays a crucial role in determining their encounters and evolutionary outcomes. This study explores how coevolution in circadian activity patterns emerges from the dynamic interplay
Rajat Kaushik   +2 more
doaj   +1 more source

Local stability properties of complex, species-rich soil food webs with functional block structure. [PDF]

open access: yesEcol Evol, 2021
de Castro F   +18 more
europepmc   +1 more source

Primal–Dual Stability in Local Optimality

open access: yesJournal of Optimization Theory and Applications
Much is known about when a locally optimal solution depends in a single-valued Lipschitz continuous way on the problem's parameters, including tilt perturbations. Much less is known, however, about when that solution and a uniquely determined multiplier vector associated with it exhibit that dependence as a primal-dual pair.
Matúš Benko, R. Tyrrell Rockafellar
openaire   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

LOCAL STABILITY OF QUASICRYSTALS

open access: yesLe Journal de Physique Colloques, 1986
The local stability of the icosahedral quasicrystals to small deformations which make them commensurate in one or more directions is considered. It is shown that icosahedral structures are generically stable to such deformations.
Biham, O., Mukamel, D., Shtrikman, S.
openaire   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Optimization of hybrid I-beams using modified particle swarm method

open access: yesИнженерно-строительный журнал, 2018
An approach for the optimization of hybrid welded I-beams based on the modification of the particle swarm method is proposed. A solution search is performed on discrete sets of variable parameters, which are taken as the size of sheets of rolled steel ...
Anatoly Alekseytsev, Mohamad Al Ali
doaj   +1 more source

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