Results 41 to 50 of about 5,240,266 (129)
Robot‐Assisted Automated Serial‐Sectioning and Imaging for 3D Microstructural Investigations
Advanced Engineering Materials, Volume 28, Issue 2, 21 January 2026.A fully automated 3D microstructure characterization platform provides new insights into materials. This robot‐assisted system performs serial‐sectioning, etching, and optical imaging to generate large‐volume 3D reconstructions with submicron resolution.
Michael Moschetti +7 more
wiley +1 more source
Sampling for stereology in lungs
European Respiratory Review, 2006 The present article reviews the relevant stereological estimators for obtaining reliable quantitative structural data from the lungs. Stereological sampling achieves reliable, quantitative information either about the whole lung or complete lobes, whilst
J. R. Nyengaard, H. J. G. Gundersen
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Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk +6 more
wiley +1 more source
Metabolic changes during cardiac regeneration in the axolotl
Developmental Dynamics, Volume 255, Issue 1, Page 66-85, January 2026.Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich +10 more
wiley +1 more source
Andrologia, Volume 2026, Issue 1, 2026.Previous studies showed considerable decrease of epididymal sperm count in diabetic rats and ascribed it to spermatogenic damage in the testis; diabetic rat models were therefore often used for pharmaceutical studies on sperm protection. But there were methodological problems with previous studies: sperm count obtained in many studies does not ...
Li Ma +7 more
wiley +1 more source
FEBS Letters, Volume 599, Issue 21, Page 3086-3102, November 2025.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Mesoscopic vascular alterations in Alzheimer's disease
Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.Abstract INTRODUCTION Cerebrovascular alterations are associated with the pathology of Alzheimer's disease (AD). Yet, the role of these alterations is not fully understood, partly due to a paucity of data from mesoscopic vasculature (24–240 µm diameter).
Mackenzie Hyman +16 more
wiley +1 more source
Journal of Comparative Neurology, Volume 533, Issue 11, November 2025.While norepinephrine is thought to act ‐ at least in part ‐ through volume transmission, evidence from cortex is limited. We quantified and compared the laminar distributions of axons immunoreactive for the norepinephrine transporter (NET, reuptake sites) and dopamine β‐hydroxylase (DBH, release sites) in primary (V1) and secondary (V2) visual cortex ...
Corey Roach +3 more
wiley +1 more source
Building Immunocompetent Cerebral Organoids From a Developmental Perspective
Glia, Volume 73, Issue 11, Page 2154-2166, November 2025.Main Points Conventional cerebral organoids do not contain microglia, which must be added. We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statistical analysis to help develop standardized protocols.
Xabier Cuesta‐Puente +8 more
wiley +1 more source
Journal of Advances in Biology & BiotechnologyThe aqueous extract of Bellucia dichotoma (AeBd) has traditionally been used in cases of snakebites and has been shown to be promising against the effects of Bothrops atrox venom (BaV).
Marissa Braga dos Anjos +6 more
semanticscholar +1 more source