Results 41 to 50 of about 3,309 (135)

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae   +53 more
wiley   +1 more source

Tyrosine Hydroxylase Deficiency Impairs TH Axonal Transport, Brain Function, and Neuronal Plasticity

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Tyrosine hydroxylase deficiency (THD) is a rare genetic disorder caused by biallelic pathogenic variants in the Th gene, leading to a deficiency in the rate‐limiting enzyme for the synthesis of dopamine (DA) and other catecholamine neurotransmitters.
Tie‐Jun Sten Shi   +6 more
wiley   +1 more source

Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1365-1386, 1 March 2026.
Abstract Uteroplacental insufficiency impairs kidney development and programs male‐onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting that the lifestyle of growth‐restricted females can have further influence on F2 kidney ...
Jessica F. Briffa   +11 more
wiley   +1 more source

Small is the New Large: Demonstration of how Microanalyses Elucidate Large‐Scale CO2 Uptake Through Mineralization

open access: yesAdvanced Sustainable Systems, Volume 10, Issue 2, February 2026.
Imaging techniques like X‐ray microcomputed tomography and electron microscopy are integrated to understand the CO2 mineralization process at the pore‐scale. These techniques are used to characterise the reaction progression in basalt. They increase the reliability of reactive transport modeling and consequently improve the CO2 storage capacity ...
Faisal W. K. Khudhur   +2 more
wiley   +1 more source

Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity

open access: yesJournal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ex vivo brain slice preparation is a popular technique in neuroscience research with many variations in preparation method. We compared two popular variations in brain slice preparation and found that the choice of brain slice preparation technique significantly affects the viability of neuronal preparation.
Felix Chan   +12 more
wiley   +1 more source

Robot‐Assisted Automated Serial‐Sectioning and Imaging for 3D Microstructural Investigations

open access: yesAdvanced Engineering Materials, Volume 28, Issue 2, 21 January 2026.
A fully automated 3D microstructure characterization platform provides new insights into materials. This robot‐assisted system performs serial‐sectioning, etching, and optical imaging to generate large‐volume 3D reconstructions with submicron resolution.
Michael Moschetti   +7 more
wiley   +1 more source

ePoster

open access: yes
European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

An Estimating the Local Deformation Parameters in Grained Structures via Stereological Methods

open access: yesIOP Conference Series: Materials Science and Engineering, 2019
S Minárik, M Martinkovič
openaire   +1 more source

Layer-specific cellular composition of mouse primary somatosensory and human temporal cortex: a direct 3D confocal counting approach. [PDF]

open access: yesFront Neuroanat
Plaza-Alonso S   +5 more
europepmc   +1 more source

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