Results 61 to 70 of about 915 (217)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Representations for continuous additive functionals of super-Brownian and super-stable processes
We study a class of continuous additive functionals for super-Brownian and super-stable processes. These are given in terms of a Tanaka-like formula that generalizes the one for local times. We give representations for these additive functionals in terms
Krone, Stephen M.
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On determining functionals for stochastic Navier-Stokes equations
, 1999 We prove the existence of a wide collection of finite sets of functionals that completely determine the long-time behaviour of solutions to 2D Navier-Stokes equations with random initial data and excited by additive white noise.
Igor D. Chueshov
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Approximation models for the continuous additive functionals of multidimensional brownian motion
A general approximation model for the continuous additive functionals of the multidimensional Brownian motion is defined by summing a family of "local" processes over the representing measure of the considered CAF.
Bally, Vlad
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On LAN for parametrized continuous periodic signals in a time inhomogeneous diffusion
, 2009 We consider a diffusion (ξ t ) t≥0 whose drift involves some T-periodic signal. T is fixed and known, whereas the signal depends on a d-dimensional parameter θ∈Θ.
Reinhard Höpfner, Yury A. Kutoyants
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Partial Linear Quantile Regression and Bootstrap Confidence Bands [PDF]
In this paper uniform confidence bands are constructed for nonparametric quantile estimates of regression functions. The method is based on the bootstrap, where resampling is done from a suitably estimated empirical density function (edf) for residuals ...
Wolfgang Karl Härdle +2 more
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