Results 151 to 160 of about 87,777 (313)

MEASURING TRANSIT SYSTEM PRODUCTIVITY AND PERFORMANCE [PDF]

open access: yes, 1982
This article summarizes the activities of the Institute of Transportation Engineer\u27s Committee 6F-22 which undertook a study of performance indicators used by transit operators, local and regional planning agencies, and state and local governments ...
Institute of Transportation Engineers
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Performance-Based Measures in Transit Fund Allocation [PDF]

open access: yes, 2004
This synthesis will be of interest to transit practitioners and transportation professionals, including technical and research staff, as well as those working with them, with regard to the use of performance measures for the allocation of financial ...
Hendren, P. G., Stanley, R. G.
core  

A Local–Transit Percolation and Clustering-Based Method for Highway Segment Importance Ranking

open access: yesSystems
The impact of disturbances on a transportation network varies depending on the location and characteristics of the affected highway segments. Given limited resources, it is crucial to prioritize the protection and repair of highway segments based on ...
Huizhe Lyu   +6 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Guidebook for Developing and Sharing Transit Bus Maintenance Practices [PDF]

open access: yes, 2005
TRB’s Transit Cooperative Research Program (TCRP) Report 109: A Guidebook for Developing and Sharing Transit Bus Maintenance Practices provides guidance on how to develop effective transit bus maintenance practices tailored to the local operating ...
Schiavone, John
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Transforming cities with transit; Transit and Land-use integrtion for sustainable urban development [PDF]

open access: yes, 2013
\u27Transforming Cities with Transit\u27 explores the complex process of transit and land-use integration in rapidly growing cities in developing countries.
Cervero, Robert   +2 more
core  

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