Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source
Intergenerational Knowledge Exchange in Japanese Biosphere Reserves: Community Perceptions from Aya and Mount Hakusan. [PDF]
Mammadova A +5 more
europepmc +1 more source
Enhanced Ionic Conductivity at the Solid Electrolyte Interphase of Oxygen‐Doped Li6PS5Cl
Machine‐learned molecular dynamics and machine‐learning‐based phase identification reveal the kinetically formed SEI at buried Li | Li6PS5Cl interfaces. The SEI is dominated by Li2S‐based anion‐substituted phases, while oxygen doping enhances SEI ionic conductivity.
Sojeong Yang +6 more
wiley +1 more source
The wisdom of crowds emerges in flocks of thousands of migrating songbirds. [PDF]
Morford J +6 more
europepmc +1 more source
A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu +9 more
wiley +1 more source
Disaster mitigation based on Minangkabau indigenous knowledge in social studies learning. [PDF]
Rahayu S +5 more
europepmc +1 more source
DDSurfer reconstructs cortical surfaces directly from diffusion MRI without requiring T1‐weighted scans. By fusing complementary microstructural features and learning diffeomorphic deformations, it efficiently generates accurate white matter and pial surfaces, improving geometric fidelity and morphometric reliability across datasets for robust surface ...
Chengjin Li +10 more
wiley +1 more source
WISDOM randomized trial comparing risk-based versus annual breast cancer screening: study cohort characteristics and design. [PDF]
Fiscalini A +42 more
europepmc +1 more source
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong +6 more
wiley +1 more source
Management of Mandibular Third Molars With an Interradicular Inferior Alveolar Nerve Using Ultrasonic Surgery: A Case Series of Three Patients. [PDF]
Scarano A +3 more
europepmc +1 more source

