Results 51 to 60 of about 34,557 (267)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Christian Muslim Moderation Local Wisdom Based

Daengku: Journal of Humanities and Social Sciences Innovation, 2022
The discussion in this study provides a statement, namely although the people in west Manggarai Regency, more precisely in Tangge Village, have different beliefs, but the differences do not make people look at it in different ways, but that is what makes the people live in harmony.
Sam'un Mukramin, Alfiani Aminah
openaire   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

What's 'Wisdom' in Local Wisdom Imaginaries on Indigenous Research?

Indigenous Southeast Asian and Ethnic Studies
The abundance of studies on local wisdom in Indonesia is evident from a Google Scholar search, which yields a wealth of resources. However, the concept of local wisdom and its distinction from related terms such as ‘local knowledge’ and ‘indigenous knowledge’ remains unclear. This article seeks to clarify the notion of ‘wisdom’ by: first, re-examining 
Rangga Kala Mahaswa, Hardiyanti Hardiyanti   +1 more
openaire   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Penilaian Persepsi Masyarakat Terhadap Bangunan Besejarah Di Koridor Kayutangan, Malang, Indonesia [PDF]

Local Wisdom, 2019
Malang is well-known for colonial buildings. Visual quality of historic buildings in the Kayutangan corridor makes it an icon of Malang City. Assessment of visual quality is affected by daytime conditions.
Baskoro Azis, Herry Santosa, Jenny Ernawati   +2 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

The Local Wisdom on Sasak Tribe Sade Hamlet Central Lombok Regency [PDF]

Local Wisdom, 2019
Traditional settlements that still survive until now one of them is in Sade Hamlet, Central Lombok Regency, NTB. This settlement is now a tourist destination because of the original architectural form of outer and inner spaces.
Adrian Widisono
doaj   +1 more source

Transmitting Local Wisdom Culture by Applying Local Wisdom-Based Comic Strips in Teaching Writing

Dharma Pendidikan, 2021
The present paper aims to know whether there is any influence of using local wisdom-based comic strips in teaching writing for the junior high school students. Local wisdom-based comic strips is a developed comic strips that contain local wisdom as the knowledge of the local people which is inherited hereditary.
openaire   +1 more source