Results 171 to 180 of about 519,807 (275)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Genome-Wide DNA Methylation Study Reveals Specific Signatures in the Affected Arterial Tissue of Patients With Giant Cell Arteritis. [PDF]

Arthritis Rheumatol
Borrego-Yaniz G, Márquez A, Estupiñán-Moreno E, Terrón-Camero LC, González-Gay MA, Castañeda S, Guggino G, Saadoun D, Lio P, Fontana S, Bonacini M, Rossi A, Cavazza A, Muratore F, Salvarani C, Pipitone N, Martin J, Croci S, Ortiz-Fernández L.   +18 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Hospital Patient and Family Advisory Councils: A Quantitative Study on How Councils are Used and Predictors of Effective Councils. [PDF]

J Patient Exp
Lewis B, Cochran C, Shoemaker S, Bhandari N, Upadhyay S, Marquez E.   +5 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Correction: Real-world use of polidocanol foam sclerotherapy for hemorrhoidal disease: insights from an international survey and systematic review with clinical practice recommendations. [PDF]

Updates Surg
Gallo G, Grossi U, De Simone V, Picciariello A, Diaco E, Fan P, He H, Li J, Lin H, La Torre M, Laforgia R, Lobascio P, Ma H, Pata F, Perinotti R, De Parades V, Pozzo M, Realis Luc A, Salgueiro P, Skowronski A, Sun P, Trompetto M, Tutino R, Wang C, Wang Z, Wang Z, Wu J, Zhang Y, Zhao S, Zeng X, Fernandes V, Moser KH, Ren D, Sileri P, Gravante G.   +34 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Equivariant Localization [PDF]

Bulletin of the London Mathematical Society, 1982
May, J. P., McClure, J., Triantafillou, G.   +2 more
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Sepsis in the emergency department: a dual challenge of early management and antimicrobial stewardship. [PDF]

BMC Infect Dis
Corsini R, Marini G, Ottone M, Rossi PG, Lattuada IM, Cocchi V, Lucchesi DMF, Cacciamani B, Beneventi S, Cantergiani S, Romani F, Simion M, Russello G, Mezzadri S.   +13 more
europepmc   +1 more source