Results 111 to 120 of about 123,352 (318)

Traduire à l’heure de la mondialisation : localisation de l’information et idéologie [PDF]

open access: yesSynergies Italie, 2016
L’une des retombées linguistiques de la mondialisation est sans aucun doute la domination de l’anglais. L’émergence des nouvelles technologies de l’information et de la communication a en revanche contribué au développement du ...
Lorenzo Devilla
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Küreselleşme ve Yerelleşme Sürecinde Bölgesel Kalkınma Ajansları

open access: yesSelçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu Dergisi, 2017
Küreselleşmeyle beraber pek çok alanda değişim ve dönüşümler meydana gelmiş, merkezi ve yerel yönetimlerde bu değişim dönüşümlerden nasibini almıştır. Merkezi yönetimlerin yapılarında bir zayıflama görülürken, yerel yönetimler de ise ortaya çıkan değişim
Mahmut Umut Ferman Akbulut   +1 more
doaj  

Localisation as Sociocultural Adaptation of Modern Design of Visual Communications

open access: yesКультура і мистецтво у сучасному світі
The aim of the article is to ground and formulate the definition of the term “localisation” in design using the example of visual communications. Results. A review of definitions and interpretations of localisation in different scientific and industrial
Natalya Udris-Borodavko, Vadym Abyzov
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Benchmarking visual SLAM methods in mirror environments

open access: yesComputational Visual Media
Visual simultaneous localisation and mapping (vSLAM) finds applications for indoor and outdoor navigation that routinely subjects it to visual complexities, particularly mirror reflections. The effect of mirror presence (time visible and its average size
Peter Herbert   +3 more
doaj   +1 more source

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