Results 171 to 180 of about 123,352 (318)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

RFID Technology for Intraoperative Localisation of Small Colorectal Tumours: Electromagnetic Analysis and Experimental Validation. [PDF]

Diagnostics (Basel)
Mocan B, Mocan M, Fulea M, Murar M, Mate Z, Calborean A, Bintintan VV.   +6 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Bio-Inspired Swarm Navigation on Resource-Constrained Robots for GPS-Denied Environments. [PDF]

Sensors (Basel)
Sheikder C, Zhang W, Chen X, Li F, He X, He H, Fan S, Tan X.   +7 more
europepmc   +1 more source

Zur Localisation des Tetrodon-Giftes

, 1890
Masako Miura, K. Takesaki
openalex   +2 more sources

Localisation

Content report on the objectrelative and global localisation system for all the platforms with a focus on accuracy and reliability with respect to the complexity of the strucure to be inspected Platformspecific sections of the deliverable will be under the responsibility of the lead partner defined in task ...
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Full-Field Assessment of Damage Evolution in Compressed Masonry with Bed Joint Reinforcement Using Digital Image Correlation. [PDF]

Materials (Basel)
Piekarczuk A, Więch P, Głodkiewicz J.
europepmc   +1 more source

Jonctions à localisation associées à un spectromètre Buechner

, 1969
G. Lemarchand, J. Quidort
openalex   +2 more sources

Evaluation of the modified S-transform for time-frequency synchrony analysis and source localisation [PDF]

, 2012
Saïd Assous, B. Boashash
openalex   +1 more source