FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Expanding the horizon: Discovery of two new spider species of the <i>Pholcus phungiformes</i> species group (Araneae, Pholcidae) from Inner Mongolia, China, with a new western record for the group. [PDF]
ZookeysYan M, Liu Y, Wang L, Yao Z.
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Revision of <i>Anadimonia</i> Ogloblin, support for synonymy with <i>Trichocerophysa</i> Gressitt & Kimoto (Coleoptera, Chrysomelidae, Galerucinae, Galerucitae), with descriptions of one new genus and nine new species. [PDF]
ZookeysLee CF, Bezděk J.
europepmc +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
The dataset of the lichen collection "Abramo Massalongo" preserved at the Natural History Museum of Venice. [PDF]
Biodivers Data JMartellos S, Seggi L, Trabucco R.
europepmc +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
2-For-1 offer: <i>Bradysia polonica</i> (Lengersdorf, 1929) and <i>Bradysia spinidensa</i> Hondru, 1968, stat. res. (Diptera, Sciaridae). [PDF]
Biodivers Data JCanty RJ +3 more
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
The José Planellas Herbarium (Herbarium BCN). [PDF]
Biodivers Data JGuardia R, Soriano I.
europepmc +1 more source