Results 171 to 180 of about 44,044 (308)

The destruction of Gaza: Satellite measurements of the economic cost of war. [PDF]

PNAS Nexus
Rinaldo D, Alazzeh R, Arcand JL, Scher C, Van Den Hoek J.   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Flexible Responses to Wildfires by Great Tits (<i>Parus major</i>) Breeding in Forests of Northeastern Algeria. [PDF]

Ecol Evol
Mennour H, Pagani-Núñez E, Bouzegag A, Bensouilah T.   +3 more
europepmc   +1 more source

Relation of Urban Transformation Projects with Locality and Their Effects on Energy Conservation: The Case of Diyarbakır

, 2019
Ceyda Duruş, Gülay Zorer Gedik
openalex   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Real-World Traffic-Polluted Air and Its Impact on a 3D Model of the Human Airway Epithelium. [PDF]

J Xenobiot
Sima M, Libalova H, Simova Z, Vrbova K, Ambroz A, Klema J, Dittrich L, Vojtisek-Lom M, Rossner P.   +8 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Hair biomonitoring reveals spatial heterogeneity of multielement exposure in Bogotá schoolchildren. [PDF]

Environ Geochem Health
Beltrán-Ardila JD, Escobar-Correa PA, Varela-Martínez DA, García-García DA, Benavidez-Piracón JA, Pinilla-Bonilla LB, Santos-Yate JD.   +6 more
europepmc   +1 more source

The actress was on the balcony, after all: Eye-tracking locality and PR-availability effects in Spanish

, 2021
Miriam Aguilar, Pilar Ferré, José M. Gavilán, José Antonio Hinojosa, Josep Demestre   +4 more
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source