Results 211 to 220 of about 1,591,314 (318)
A Pose Initialization Method for Unmanned Vehicles Based on an Improved Siamese Neural Network and Multi-Stage Probabilistic Registration Localization. [PDF]
Sensors (Basel)Yang J, Chen B, Shen W, Xu X.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Precise tactile localization on tools in two dimensions. [PDF]
iScienceLongo MR +4 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Health-related quality of life after thulium fiber laser lithotripsy: a prospective study according to stone localization. [PDF]
Sci RepAlbaz AC +4 more
europepmc +1 more source
Translation strategies in video game localization: study of the Italian version of Undertale
openIn this paper I am going to analyze the translation strategies used in video game localization, taking care to underline the importance of transcreation and audiovisual translation in the localization process. The video game Undertale (2015), by Toby
MANFRIN, ELETTRA
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Preoperative imaging strategies to optimize surgical treatment in primary hyperparathyroidism (pHPT). [PDF]
BMC SurgFries F +11 more
europepmc +1 more source