Results 251 to 260 of about 1,591,314 (318)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Maspin Modulates Malignant Phenotypes Depending on Subcellular Localization in Pancreatic Ductal Adenocarcinoma Cell Lines. [PDF]

Cancers (Basel)
Mochida H, Sakabe T, Shingu T, Makishima K, Umekita Y.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Pre-Stimulus Head Position and Its Effect on Sound Localization Metrics in Children. [PDF]

Audiol Res
Zangerl E, Muigg F, Seebacher J, Graf S, Zelger P.   +4 more
europepmc   +1 more source

Local Councillors Between Local "Government" and Local "Governance"

, 1999
openaire   +2 more sources

Conserved RNA helicase Vasa regulates ribonucleoprotein condensate dynamics and mRNA localization. [PDF]

iScience
Tian S, Kim H, Curnutte HA, Trcek T.
europepmc   +1 more source

Mammogram geometric projection localization (MaGPL) for surgical body-surface localization of nonpalpable breast calcifications. [PDF]

Gland Surg
Chen X, Lin X, Liang B, Xu Y, Lin J, Zhang Y, Zhang Y, Guo L, Huang J, Ding Z, Huang R, Kong Q, Zhang F, Liu H, Chen Y, Zhang G, Wang Y.   +16 more
europepmc   +1 more source

Blockchain-Enabled Uncertainty-Aware Passive Wi-Fi Localization for Secure Critical Infrastructure Sensor Networks. [PDF]

Sensors (Basel)
Prokopovych-Tkachenko D, Galushchenko O, Torstensson O, Zvieriev V, Adilzhanova S, Pignaton de Freitas E.   +5 more
europepmc   +1 more source