Results 281 to 290 of about 3,003,975 (343)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Artificial Intelligence-Assisted Detection of Canine Impaction, Localization, and Classification from Panoramic Images: A Diagnostic Accuracy Comparative Study with CBCT. [PDF]

Children (Basel)
Helal NM, Aljehani AF, Alomari SA, Mahmoud RA, Khalifa HM.   +4 more
europepmc   +1 more source

Local Councillors Between Local "Government" and Local "Governance"

, 1999
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Evaluation of Epithelial Integrity in Human Precision-Cut Kidney Slices. [PDF]

APMIS
Pedersen GA, Green BB, Merrild C, Elsborg SH, Madsen MG, Keller AK, Mutsaers HAM, Nørregaard R, Nejsum LN.   +8 more
europepmc   +1 more source

Improved Source Localization of Auditory Evoked Fields using Reciprocal BEM-FMM. [PDF]

Brain Topogr
Drumm DA, Ponasso GN, Linke A, Ganguly S, Wang A, Noetscher GM, Maess B, Knösche TR, Haueisen J, Lewine JD, Abbott CC, Makaroff SN, Deng ZD.   +12 more
europepmc   +1 more source

5-Azacitidine Partially Resets the Subcellular Localization of YAP in Human Bone Marrow-Derived Mesenchymal Stem Cells. [PDF]

Cells
Takayama H, Kishi H, Kobashi G.
europepmc   +1 more source