Results 31 to 40 of about 42,506 (251)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature
Pediatric Blood &Cancer, EarlyView.ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi +7 more
wiley +1 more source
A three-dimensional linear analysis of steady ship motion in deep water [PDF]
, 1986 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The investigation of steady ship motion in calm water is a classic problem in ship hydrodynamics, where ship waves and wave resistance are subjects of ...
Baar, J.M, Baar, Job
core
Computational and Mathematical MethodsThis research explores the fractional dynamics of two important nonlinear models: the (2+1)-dimensional breaking soliton equation, which arises in the description of various physical phenomena such as shallow-water waves, plasma oscillations, and optical
Weerachai Thadee +4 more
doaj +1 more source
South African Journal of Chemical EngineeringNatural convection within enclosed cavities plays a critical role in heat and mass transfer across a wide range of engineering applications. Buoyancy flows are a fundamental aspect of many optimized systems currently deployed, including passive cooling ...
Asif Hasan +5 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Inhibition of pitting on carbon steel [PDF]
, 2011 Carbon dioxide and hydrogen sulphide pitting related failures are a prime concern in oil and gas internal pipelines. Often, these types of failure have a great impact on safety and environmental matters and can cause severe financial consequences to the
Ismail, Ismarullizam Mohd
core
A General Finite Beam on Tensionless Foundation Model for Rail Track Characterization and Evaluation
SensorsRail infrastructure plays an important role in freight and passenger mobility, and the assessment of rail track structure depends critically on understanding how the rail interacts with the supporting foundation.
Hamoud H. Alshallaqi, Brett A. Story
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source