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Localized Scleroderma of the Face
2013Localized scleroderma (LS), also known as morphea, is the most frequent form of scleroderma in childhood and is grouped into five subtypes: circumscribed morphea, linear scleroderma, generalized morphea, pansclerotic morphea, and a mixed subtype, where a combination of two or more of the previous subtypes is present.
Zulian F, Trainito S, Belloni Fortina A
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Dermatologic therapy, 2012
Localized scleroderma (also called morphea) is a term encompassing a spectrum of sclerotic autoimmune diseases that primarily affect the skin, but also might involve underlying structures such as the fat, fascia, muscle, and bones. Its exact pathogenesis is still unknown, but several trigger factors in genetically predisposed individuals might ...
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Localized scleroderma (also called morphea) is a term encompassing a spectrum of sclerotic autoimmune diseases that primarily affect the skin, but also might involve underlying structures such as the fat, fascia, muscle, and bones. Its exact pathogenesis is still unknown, but several trigger factors in genetically predisposed individuals might ...
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Glycosaminoglycans in Localized Scleroderma (Morphoea)
Connective Tissue Research, 1985The composition of glycosaminoglycans (GAGs) was analyzed in skin samples of eight patients suffering from localized scleroderma, i.e., three having generalized morphoea and five localized morphoea plaques. From each patients, biopsies were obtained from sclerotic and perilesional areas, and from clinically uninvolved skin of the same region.
R, Møller, J, Serup, T, Ammitzbøll
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Archives of Dermatology, 1966
A case of linear and morphea scleroderma is reported. Histochemical studies revealed an increase of positive PAS material, diastase resistant, in the areas of homogenized collagen. Chemical analysis suggests an increase in hexoses and hexosamines, probably bound to the collagen fibers.
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A case of linear and morphea scleroderma is reported. Histochemical studies revealed an increase of positive PAS material, diastase resistant, in the areas of homogenized collagen. Chemical analysis suggests an increase in hexoses and hexosamines, probably bound to the collagen fibers.
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Borrelia burgdorferi and Localized Scleroderma
Archives of Dermatology, 1989To the Editor.— Aberer et al, 1 in Austria, have suggested that morphea might be related to Borrelia burgdorferi infection. These authors found antibodies to B burgdorferi in five of ten patients with morphea in one study and eight of 15 patients in another study, which used the enzyme-linked immunosorbent assay.
V, Lecerf +4 more
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Systemic manifestations in localized scleroderma
Current Rheumatology Reports, 2004In this paper, the various systemic manifestations reported in localized scleroderma, their incidence, their relationship with systemic sclerosis, and their relationship with other autoimmune or connective tissue diseases will be analyzed.
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New developments in localized scleroderma
Current Opinion in Rheumatology, 2008Localized scleroderma, also known as morphea, is the most frequent form of scleroderma in childhood. Early diagnosis, appropriate assessment and effective treatment may improve the long-term outcome.Recent studies, regarding the microchimerism theory or the mechanism of action of phototherapy, have yielded important information on the disease ...
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Longitudinal melanonychia in localized scleroderma
Journal of the American Academy of Dermatology, 2004Longitudinal melanonychia associated with scleroderma is rare. This is paradoxical, as increased skin pigmentation is frequent in the latter disease. This article reports 4 cases of longitudinal melanonychia that were found concurrently with various types of localized scleroderma.
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Morphea (Localized Scleroderma)
The Journal of Pediatrics, 2007Lisa, Weibel +2 more
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