Results 211 to 220 of about 17,204 (266)

Protective effects of swimming exercise on experimental rheumatoid arthritis in rats through modulation of leptin receptor expression and inflammation. [PDF]

open access: yesTurk J Phys Med Rehabil
Yavaş Durasıllı T   +8 more
europepmc   +1 more source

Tree shrew model of early diabetic retinopathy reveals microvascular dysfunction and identifies phosphoserine aminotransferase 1 as a novel therapeutic target

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We developed an animal model of early diabetic retinopathy (DR) in the tree shrew by feeding a high‐fat and high‐sugar diet in combination with STZ. Physiological and biochemical index detection, hematoxylin and eosin staining, and transmission electron microscopy were performed to examine DR.
Min Qiu   +10 more
wiley   +1 more source

Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry

open access: yesAngewandte Chemie, EarlyView.
Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang   +7 more
wiley   +1 more source

Staged Diversity‐Constrained Machine Learning for High‐Dimensional Reaction Condition Optimization

open access: yesAngewandte Chemie, EarlyView.
Staged diversity‐constrained modeling enables efficient navigation of high‐dimensional reaction spaces, validated on cross‐coupling HTE data and applied to ruthenium‐catalyzed meta‐C─H functionalization. ABSTRACT Optimizing reaction conditions in high‐dimensional chemical spaces remains a central challenge in modern synthesis.
Shu‐Wen Li   +5 more
wiley   +1 more source

Conformational changes in the motor ATPase CpaF facilitate a rotary mechanism of Tad pilus assembly. [PDF]

open access: yesNat Commun
Yen IY   +5 more
europepmc   +1 more source

CNS Myelin Sheath Lengths Locally Scale to Axon Diameter via Piezo1

open access: yes
Young AR   +7 more
europepmc   +1 more source

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