Results 221 to 230 of about 5,997,295 (267)

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Short-Course Radiotherapy Combined With CapeOx and PD-1 Inhibitor Following Local Excision in High-Risk Early Rectal Cancer: Study Protocol for a Prospective Phase II Trial (TORCH-LE). [PDF]

open access: yesClin Med Insights Oncol
Wang J   +14 more
europepmc   +1 more source

Locally Graded Quotients of Locally Graded Groups

open access: yesCommunications in Algebra, 2009
A group G is said to be locally graded if every nontrivial, finitely generated subgroup of G has a nontrivial finite image. Every group can occur as a quotient of a locally graded group. It is shown that the largest subgroup and quotient closed interior of the class of locally graded groups is the class of groups in which every simple quotient of every
Maria Tota
exaly   +3 more sources

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