Results 41 to 50 of about 25,264 (249)

On difficult problems and locally graded groups

Journal of Mathematical Sciences, 2007
A group \(G\) is called an LG-group if any non-trivial finitely generated subgroup in \(G\) has a proper subgroup of finite index. It is known that the class of LG-groups is closed with respect to taking subgroups, extensions and Cartesian products. This class also contains all groups whose finitely generated subgroups are LG-groups and all groups that
openaire   +3 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Grading of homogeneous localization by the Grothendieck group

, 2023
Let $G$ be the Grothendieck group of a commutative monoid $M$. We prove that for any multiplicative set $S$ of homogeneous elements of an $M$-graded ring $R=\bigoplus\limits_{m\in M}R_{m}$, then the localization ring ...
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Groups with the Infinite Non-Quasicentral Nodal Subgroup

Communications, 2014
We present some properties of the groups with the infinite non-quasicentral periodic nodal subgroup. Our main results are formulated in Theorem 1, 2 and Theorem 3, 4.
Ludovit Tomanek, Anna Tomankova
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Dose-Dependent Amelioration of Protein-Energy Malnutrition in Rats by Trigonella foenum-graecum Seed Supplementation

UMYU Journal of Microbiology Research
Protein-Energy Malnutrition (PEM) is most prevalent in low- and middle-income countries, where 45% of child deaths were attributed to under-nutrition.  Trigonella foenum-graecum (fenugreek) seed is known for its important phytonutrients.
Lambe, M. O., Sulyman, R. A., Akanmu, Z. I., Muhammad, K. T., Abdullahi, S., Chidolu, C. K.   +5 more
doaj   +1 more source

Antireflux versus conventional self-expanding metallic Stents (SEMS) for distal esophageal cancer: results of a multicenter randomized trial

Endoscopy International Open, 2016
Introduction: Self-expanding metal stents (SEMS) are commonly used in the palliation of dysphagia in patients with inoperable esophageal carcinoma. However, they predispose to gastroesophageal reflux when deployed across the gastroesophageal junction ...
E. Coron, G. David, S. Lecleire, J. Jacques, A. Le Sidaner, T. Barrioz, D. Coumaros, C. Volteau, B. Vedrenne, P. Bichard, C. Boustière, Y. Touchefeu, J. Brégeon, F. Prat, M. Le Rhun   +14 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source