Results 201 to 210 of about 2,942 (253)

Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism

open access: yesCell Proliferation, EarlyView.
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang   +11 more
wiley   +1 more source

Perception of Performance Measurement Systems: The Case of Control Rooms Implemented in Health Organizations

open access: yesFinancial Accountability &Management, EarlyView.
ABSTRACT This study examines the perception of control rooms, a performance measurement system (PMS) derived from Lean management adopted in Québec's public sector. Our main objective is to understand how managers perceive this new PMS within a context of existing accountability controls.
Émilie Portelance   +2 more
wiley   +1 more source

Family dynamics and death row: A dual‐theory approach

open access: yesFamily Relations, EarlyView.
ABSTRACT Objective This study investigates how the incarceration and death sentence of a loved one impact family dynamics in Malaysia, drawing on restorative justice and family systems theories. Background Despite the global movement toward abolishing the death penalty, Malaysia continues to impose discretionary death sentences for crimes such as ...
Reyhaneh Bagheri
wiley   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

open access: yesThe FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek   +12 more
wiley   +1 more source

Beyond Confessional Cultures: Identity and the Role of Silence in Diversity, Equity, and Inclusion Interventions

open access: yesGender, Work &Organization, EarlyView.
ABSTRACT This paper interrogates the confessional foundations of Diversity, Equity, and Inclusion (DEI) work, which have emerged predominantly from Global North traditions rooted in Christian understandings of subjectivity. In such traditions, identity is asserted through self‐declaration, visibility, and vocal articulation of difference, what we term ...
Claudia Eger, Mustafa F. Özbilgin
wiley   +1 more source

High prevalence of loss of Claudin‐18 expression in invasive non‐mucinous lung adenocarcinoma: Potential diagnostic implications in routine practice

open access: yesHistopathology, EarlyView.
Loss of Claudin‐18 (Cldn18) expression is a frequent and specific feature of non‐mucinous lung adenocarcinoma (NM‐LUAD). Cldn18 immunohistochemistry may serve as an ancillary tool for distinguishing malignant from non‐neoplastic alveolar epithelium, as well as for differentiating NM‐LUADs with mucin production from M‐LUADs, particularly in small or ...
Stefano Lucà   +18 more
wiley   +1 more source

Engaging With Policymakers and Practitioners to Implement Restorative Justice in Europe: Lessons From 10 Countries in Restorative Justice: Strategies for Change

open access: yesThe Howard Journal of Crime and Justice, EarlyView.
ABSTRACT Research suggests that enabling greater participation in restorative justice can lead to strong social, health and economic benefits for people who commit offences, victims, communities and states. Yet, restorative justice remains partially implemented in Europe and many people cannot easily access services in practice, even in countries with ...
Ian D. Marder   +4 more
wiley   +1 more source

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