Results 131 to 140 of about 18,792,309 (313)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Learning from Location Histories for Context-aware Location Recommendations in LBS
Location recommendation is one of the most important components in many Location Based Services (LBS), especially in mobile guides. Currently, providing context-aware location (e.g., Point of Interest, POI) recommendations is still very challenging. This
Huang, Haosheng, Gartner, Georg
core
Location-based clicking components and grade correlation.
Location-based clicking components and grade correlation.
Ryan L. Boyd (5509349) +2 more
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
An agent-based location evaluation model
Truck transportation is considered as a favourable mode by shippers to carry freight at most ranges of distance as it has more flexibility in fleet size, capacity, scheduling, routing, and access.
Sirikijpanichkul, Ackchai
core
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Location-based mobile marketing innovations
The increasing complexity of the industry means that marketers must now be experts not only in marketing but also in people, data, delivery platforms, and mobile location-based marketing. The objective of location-based marketing via mobile devices is to
Yim, J (15773000) +2 more
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
An Agent-based Model of Retail Location with Complementary Goods [PDF]
This paper examines the emergence of retail clusters on a supply chain network comprised of suppliers, retailers, and consumers. An agent-based model is proposed to investigate retail location distribution in a market of two complementary goods.
Arthur Huang, David Levinson
core
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source

