Results 181 to 190 of about 18,792,309 (313)

Ethical and Political Responsibility in Location Based Services - The Need of Implementing Ethical Thinking in Our Research Field

open access: yes, 2014
Rapid technical developments in Location Based Services (LBS) lead to new applications and possibilities in many personal and institutional sectors. LBS became a powerful instrument in predicting consumer behaviour and preventing crime.
Retscher, Günther, Obex, Franz
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Privacy implications of location and contextual data on the social web

open access: yes, 2011
Location-based applications have recently begun to emerge on the Social Web. After their appearance numerous concerns with regards to location privacy have been provoked.
Millard, David   +3 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Blockchain enabled privacy provisioning scheme for location based services in VANETs. [PDF]

open access: yesPLoS One
Ilyas I   +6 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Mind your step! : How profiling location reveals your identity - and how you prepare for it

open access: yes, 2006
Location-based services (LBS) are services that position your mobile phone to provide some context-based service for you. Some of these services – called ‘location tracking’ applications - need frequent updates of the current position to decide whether a
Fritsch, Lothar
core  

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