Results 31 to 40 of about 437,026 (247)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Dummy-Based User Location Anonymization Under Real-World Constraints

open access: yesIEEE Access, 2016
According to the growth of mobile devices equipped with a GPS receiver, a variety of location-based services (LBSs) have been launched. Since location information may reveal private information, preserving location privacy has become a significant issue.
Takahiro Hara   +4 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Using location semantics to realize personalized road network location privacy protection

open access: yesEURASIP Journal on Wireless Communications and Networking, 2020
With the rapid development of location-based services in the field of mobile network applications, users enjoy the convenience of location-based services on one side, and they are exposed to the risk of privacy disclosure on the other side. Attackers may
Li Kuang   +4 more
doaj   +1 more source

Achieving User-Defined Location Privacy Preservation Using a P2P System

open access: yesIEEE Access, 2020
As location-based services become widely used in daily life, there is growing concern in preserving location privacy of users to avoid that attackers infer information about users by collecting and analyzing requests initiated by users.
Shengchao Liu   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

An Improved Anonymous Authentication Protocol for Location-Based Service

open access: yesIEEE Access, 2019
The authentication protocols are implemented to provide identity authentication for communication entities. With the increasing demand of network security and the development of technology, the anonymous authentication protocol for LBS (location based ...
Cao Shouqi   +4 more
doaj   +1 more source

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