Results 51 to 60 of about 426,488 (244)

Noise-Resilient Acoustic Low Energy Beacon for Proximity-Based Indoor Positioning Systems

open access: yesSensors, 2021
Proximity-Based Indoor Positioning Systems (PIPSs) are a simple to install alternative in large facilities. Besides, these systems have a reduced computational cost on the mobile device of those users who do not continuously demand a high location ...
Teodoro Aguilera   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Location-Based Services

open access: yes, 2006
Location-based services are expected to play an integral role in the mobile-commerce domain. Mobile network operators and service providers have the opportunity to add value and create additional revenue streams through a variety of personalized services based on location of individual wireless users.
Priggouris, I.   +2 more
  +5 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

NON-TAYLOR SERIES BASED POSITIONING METHOD FOR LOCATION BASED SERVICES

open access: yesJournal of ICT, 2008
Location Based Services (LBS) has gained increasing popularity in major cities. Due to blocking from man-made structures, the existing Global Positioning System (GPS) could not satisfy LBS applications, especially in street canyon and indoor surroundings.
Tan Kim Geok   +2 more
doaj   +3 more sources

A Novel Location Privacy-Preserving Approach Based on Blockchain

open access: yesSensors, 2020
Location-based services (LBS) bring convenience to people’s lives but are also accompanied with privacy leakages. To protect the privacy of LBS users, many location privacy protection algorithms were proposed.
Ying Qiu, Yi Liu, Xuan Li, Jiahui Chen
doaj   +1 more source

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