Results 71 to 80 of about 28,440,571 (273)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

WiKaF - A knowledge-based Kalman-Filter for pedestrian positioning

open access: yes, 2007
The precise, reliable and preferably everywhere available positioning of mobile users is a substantial precondition for the provision of location and situation based information by Location Based Services.
Reiterer, Alexander   +2 more
core   +2 more sources

NON-TAYLOR SERIES BASED POSITIONING METHOD FOR LOCATION BASED SERVICES

open access: yesJournal of ICT, 2008
Location Based Services (LBS) has gained increasing popularity in major cities. Due to blocking from man-made structures, the existing Global Positioning System (GPS) could not satisfy LBS applications, especially in street canyon and indoor surroundings.
Tan Kim Geok   +2 more
doaj   +3 more sources

A Novel Location Privacy-Preserving Approach Based on Blockchain

open access: yesSensors, 2020
Location-based services (LBS) bring convenience to people’s lives but are also accompanied with privacy leakages. To protect the privacy of LBS users, many location privacy protection algorithms were proposed.
Ying Qiu, Yi Liu, Xuan Li, Jiahui Chen
doaj   +1 more source

Economic location-based services, privacy and the relationship to identity [PDF]

open access: yes, 2005
Mobile telephony and mobile internet are driving a new application paradigm: location-based services (LBS). Based on a person’s location and context, personalized applications can be deployed.
Fritsch, Lothar
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Improving YOLOv8 with parallel frequency channel attention for taxi passengers

open access: yesIET Image Processing
Detecting taxi passengers is crucial for assessing taxi driver behavior, which plays a significant role in regulating the taxi industry. Despite the advancements in deep learning, object detection algorithms have not been extensively applied to this ...
Qi Gao, Di He, Guilin Xu
doaj   +1 more source

Learning from Location Histories for Context-aware Location Recommendations in LBS

open access: yes, 2013
Location recommendation is one of the most important components in many Location Based Services (LBS), especially in mobile guides. Currently, providing context-aware location (e.g., Point of Interest, POI) recommendations is still very challenging. This
Huang, Haosheng, Gartner, Georg
core   +4 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy