Results 81 to 90 of about 424,320 (246)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
ABC Journal of Advanced Research, 2019 In the current information technology trend, GIS (Geographic Information Systems) and GPS (Global Positioning Systems) are potential systems providing convenient, valuable services. They are a fundamental base in location-based services (LBS). LBS is an object positioning and monitoring system with a major combination of advanced technologies such as ...
Huynh Tan Hoi, Le Vu Truong
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
IEEE Access, 2018 Cognitive radio and non-orthogonal multiple access are promising for alleviating the severe spectral scarcity problem encountered by the next generation wireless communication systems.
Yuhao Wang +5 more
doaj +1 more source
Heterogeneous deniable authenticated encryption for location-based services. [PDF]
PLoS One, 2021 Jin C, Kan G, Chen G, Yu C, Jin Y, Xu C.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Location Based Services (LBS) for Searching Tire Repair Location in Banjarbaru City Based on Android
Jurnal Fisika Flux, 2019 The tire repair location is one of the determining factors sought by motorized vehicle users if they are experiencing a tire leak in the middle of a trip.
Desy Ika Puspitasari +1 more
doaj +1 more source
Spatiotemporal Mobility Based Trajectory Privacy-Preserving Algorithm in Location-Based Services. [PDF]
Sensors (Basel), 2021 Xu Z, Zhang J, Tsai PW, Lin L, Zhuo C.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source