Results 81 to 90 of about 2,453,654 (328)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Implementing a map based simulator for the location API for J2ME [PDF]

open access: yes, 2005
The Java Location API for J2METM integrates generic positioning and orientation data with persistent storage of landmark objects. It can be used to develop location based service applications for small mobile devices, and these applications can be ...
Parsons, D.
core  

Cloud Based Application Development for Accessing Restaurant Information on Mobile Device using LBS

open access: yes, 2011
Over the past couple of years, the extent of the services provided on the mobile devices has increased rapidly. A special class of service among them is the Location Based Service(LBS) which depends on the geographical position of the user to provide ...
Shetty, Keerthi S., Singh, Sanjay
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

ADVANCED PERSONALIZATION OF LOCATION BASED SERVICES [PDF]

open access: yes
This article explores possible solutions for improving Location Based Services (LBS). For the purpose of this paper context, user profile, previous choices and the choice profiles of similar users are aspects taken into consideration.
LIVIU COTFAS
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Navigating MazeMap: indoor human mobility, spatio-logical ties and future potential

open access: yes, 2014
Global navigation systems and location-based services have found their way into our daily lives. Recently, indoor positioning techniques have also been proposed, and there are several live or trial systems already operating.
Biczok, Gergely   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Distributed and adaptive location identification system for mobile devices

open access: yesEURASIP Journal on Advances in Signal Processing, 2018
Indoor location identification and navigation need to be as simple, seamless, and ubiquitous as its outdoor GPS-based counterpart is. It would be of great convenience to the mobile user to be able to continue navigating seamlessly as he or she moves from
Fahed Awad   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy