Results 131 to 140 of about 699,381 (334)

Transportation networks and the location of human activities [PDF]

The impact of transportation networks on the location of human activities is a surprisingly neglected topic in economic geography. Using the simple plant location problem, this paper investigates such an impact in the case of a few idealized networks. It
Dominique Peeters, Isabelle Thomas, Jacques Thisse   +2 more
core  

Some challenges for ethics in social network research

, 2015
This work was supported by the Engineering and Physical Sciences Research Council [grant numbers EP/J500549/1, EP/M506631/1].Social network sites (SNSes) comprise one of the most popular networked applications of late, with hundreds of millions of users.
Hutton, Luke, Henderson, Tristan, Luke Hutton, Tristan Henderson   +3 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Tag disambiguation based on social network information

, 2011
Within 20 years the Web has grown from a tool for scientists at CERN into a global information space. While returning to its roots as a read/write tool, its entering a more social and participatory phase.
Qasim, Syed Sumair
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Practical privacy and security for opportunistic networks

, 2014
When in physical proximity, data can be directly exchanged between the mobile devices people carry - for example over Bluetooth. If people cooperate to store, carry and forward messages on one another's behalf, then an opportunistic network may be formed,
Parris, Iain
core  

Identifying Travel Regions Using Location-Based Social Network Check-in Data. [PDF]

Front Big Data, 2019
Sen A, Dietz LW.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Integrating trust with public reputation in location-based social networks for recommendation making

, 2008
The recent emergence of location-based social\ud networking services is revolutionizing web-based social\ud networking allowing users to share real-life\ud experiences via geo-tagged user-generated multimedia\ud content.
Touhid Bhuiyan, Josang, Audun, Bhuiyan, Touhid, Yue Xu, Xu, Yue, Audun Jøsang   +5 more
core   +1 more source