Results 71 to 80 of about 1,010,893 (298)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

An anonymous entropy-based location privacy protection scheme in mobile social networks

open access: yesEURASIP Journal on Wireless Communications and Networking, 2019
The popularization of mobile communication devices and location technology has spurred the increasing demand for location-based services (LBSs). While enjoying the convenience provided by LBS, users may be confronted with the risk of privacy leakage.
Lina Ni   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

USERS ACCEPTANCE OF LOCATION-BASED MARKETING APPS IN TOURISM SECTOR: AN EXPLORATORY ANALYSIS [PDF]

open access: yesJournal of Spatial and Organizational Dynamics, 2018
Mobile devices are the most used technology tools to access the Internet since they allow access from anywhere. This possibility has prompted companies to focus, to a greater extent, strategies based on geolocation marketing.
Pedro Palos-Sanchez   +3 more
doaj  

Regularising Factorised Models for Venue Recommendation using Friends and their Comments [PDF]

open access: yes, 2016
Venue recommendation is an important capability of Location-Based Social Networks such as Yelp and Foursquare. Matrix Factorisation (MF) is a collaborative filtering-based approach that can effectively recommend venues that are relevant to the users ...
Macdonald, Craig   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Reading the social preferences of tourist destinations through social media data [PDF]

open access: yes, 2016
The social preferences of individuals have been traditionally identified through traditional means using field techniques such as direct interviewing, observation and people-counting.
Martí, Pablo   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Where could we go? Recommendations for groups in location-based social networks [PDF]

open access: yes, 2017
| openaire: EC/H2020/654024/EU//SoBigDataLocation-Based Social Networks (LBSNs) enable their users to share with their friends the places they go to and whom they go with. Additionally, they provide users with recommendations for Points of Interest (POI)
Ayala-Gomez, F   +4 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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