Results 241 to 250 of about 3,756,771 (293)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Submucosal Tunneling Endoscopic Resection for Upper Gastrointestinal Subepithelial Lesions: Development of a Digital Nomogram. [PDF]

Endosc Int Open
Aslan F, Ozer S, Aktas O, Odemis SE.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

The impact of environmental factors, sowing time, and soil conditions on the growth, yield, and resilience of Fagopyrum tataricum and Fagopyrum esculentum in Egyptian agroecosystems. [PDF]

PLoS One
M Hassona M, Morsy NM, Hussein AMS, Abd El-Aal HA.   +3 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Location, Location, Location

Minnesota medicine, 2012
openaire   +3 more sources

Modeling recreational visitation at Bureau of Land Management sites. [PDF]

Sci Rep
Hanson D, Wood SA, Rappaport S, Wilkins EJ, Schuster RM.   +4 more
europepmc   +1 more source

Along- and Cross-Track Relocation for Ground Moving Target in a Squint Multichannel SAR System. [PDF]

Sensors (Basel)
Huang Z, Liu A, Zhang R, Li L, Cai J.
europepmc   +1 more source