Results 81 to 90 of about 4,496,087 (288)
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Energy and Accuracy Trade-Offs in Accelerometry-Based Activity Recognition [PDF]
Driven by real-world applications such as fitness, wellbeing and healthcare, accelerometry-based activity recognition has been widely studied to provide context-awareness to future pervasive technologies.
Geoff V. Merrett +7 more
core +1 more source
A Middleware Architecture for Integrating Privacy Preferences and Location Accuracy [PDF]
Location-Based Access Control (LBAC) systems support the evaluation of conditions on locations in the enforcement of access control policies. The ability to evaluate conditions on a set of authorized locations has a number of well-known advantages, including enriching access control expressiveness.
C.A. Ardagna +4 more
openaire +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Optimized Geographic Routing in Mobile Ad Hoc Network Using Gray Wolf Optimization
The geographic routing protocol (GRP) in general seeks the location of sensor nodes to decide the routing path in mobile ad hoc network. This increases the routing overhead while finding the location of nodes.
Vimalnath S., Ravi G.
doaj +1 more source
Location Accuracy of Commercial IP Address Geolocation Databases
This paper deals with finding the geographical location of Internet nodes remotely with no need to communicate with the nodes located (client-independently). IP geolocation is used in a number of areas, such as content personalisation, on-line fraud prevention and detection, and digital media law enforcement. One of the main concerns when studying the
Dan Komosny +2 more
openaire +5 more sources
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Exploration on Increasing Packet delivery rate in WSN using Cluster Approach
Wireless Sensor Network (WSN) plays a vital role and part of real time communication applications. Location of unknown node is difficult to find in the presence of mobile sensor nodes.
R. Mahaveerakannan +2 more
doaj +1 more source

