Results 121 to 130 of about 1,017,250 (273)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Choice Rules with Size Constraints for Multiple Criteria Decision Making [PDF]
In outranking methods for Multiple Criteria Decision Making (MCDM), pair-wise comparisons of alternatives are often summarized through a fuzzy preference relation.
Alfandari, Laurent
core +1 more source
Abstract Structural topology optimization is usually performed with predetermined support conditions. In this chapter, we present a general method for optimizing support locations and show how it can be integrated with topology optimization.
openaire +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A Discrete Particle Swarm Optimization Algorithm for Bi-Criteria Warehouse Location Problem [PDF]
The uncapacitated warehouse location problem (UWLP) is one of the widely studied discrete location problems, in which the nodes (customers) are connected to a number (w) of warehouses in such a way that the total cost, yields from the dissimilarities ...
Fehmi Burcin Ozsoydan, Tugba Sarac
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Iranian Journal of Public Health, 2013 Background: Location-allocation is a combinatorial optimization problem, and is defined as Non deterministic Polynomial Hard (NP) hard optimization. Therefore, solution of such a problem should be shifted from exact to heuristic or Meta heuristic due to ...
Hasan Aghamohammadi +3 more
doaj +2 more sources
Product innovation and logistic optimization in a novel urban-type model [PDF]
We consider the strategic choice between product innovation and logistic optimization in a novel urban framework where consumers are distributed across the city and have different incomes depending on their location in the town. Depending on the relative
Luigi Filippini, Stefano Colombo
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source