Results 131 to 140 of about 405,909 (257)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

A refined maximum predictability for next location prediction with fusion knowledge. [PDF]

PLoS One
Huang L, He Z, Li X, Yu Z.
europepmc   +1 more source

A geographical location prediction method based on continuous time series Markov model. [PDF]

PLoS One, 2018
Du Y, Wang C, Qiao Y, Zhao D, Guo W.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Optimize a chain convenience store location prediction model by using MTS-machine learning methodology. [PDF]

Sci Rep
Ou TY, Fu HP, Wu MZ.
europepmc   +1 more source

A user-generated data based approach to enhancing location prediction of financial services in sub-Saharan Africa. [PDF]

Appl Geogr, 2019
McKenzie G, Slind RT.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Electrical stimulation-based nerve location prediction for cranial nerve VII localization in acoustic neuroma surgery. [PDF]

Brain Behav, 2018
Puanhvuan D, Chumnanvej S, Wongsawat Y.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

SuperMetal: a generative AI framework for rapid and precise metal ion location prediction in proteins. [PDF]

J Cheminform
Lin X, Su Z, Liu YL, Liu J, Kuang X, Cummings PT, Spencer-Smith J, Meiler J.   +7 more
europepmc   +1 more source