Results 121 to 130 of about 4,098,217 (236)
Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery
Advanced Science, EarlyView.Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie +11 more
wiley +1 more source
The Value of Online Information Privacy: An Empirical Investigation [PDF]
Concern over online information privacy is widespread and rising. However, prior research is silent about the value of information privacy in the presence of potential benefits from sharing personally identifiable information.
Hann, Il-Horn +3 more
core
A fine granularity based user collaboration algorithm for location privacy protection. [PDF]
PLoS One, 2019 Wang B, Zhang L, Zhang G.
europepmc +1 more source
Advanced Science, EarlyView.Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu +12 more
wiley +1 more source
Location Privacy Protection in Distributed IoT Environments Based on Dynamic Sensor Node Clustering. [PDF]
Sensors (Basel), 2019 Dimitriou K, Roussaki I.
europepmc +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Advanced Science, EarlyView.Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
A Blockchain-Based Location Privacy Protection Incentive Mechanism in Crowd Sensing Networks. [PDF]
Sensors (Basel), 2018 Jia B, Zhou T, Li W, Liu Z, Zhang J.
europepmc +1 more source
Advanced Science, EarlyView.Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu +12 more
wiley +1 more source
SPS and DPS: Two New Grid-Based Source Location Privacy Protection Schemes in Wireless Sensor Networks. [PDF]
Sensors (Basel), 2019 Wang Q, Zhan J, Ouyang X, Ren Y.
europepmc +1 more source
Advanced Science, EarlyView.LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao +13 more
wiley +1 more source