Results 81 to 90 of about 852,574 (290)

Hybrid Model for Point-of-Interests Recommendation Based on Time Effect [PDF]

open access: yesJisuanji gongcheng, 2019
In Location-Based Social Networks(LBSNs),real-time recommendation data of Point-of-Interests(POIs) and check-in data of users are highly sparse.Therefore,a hybrid recommendation model based on time effect is proposed.Through the data model of potential ...
ZHANG Qishan, LI Ke, LIN Xiaorong
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Location-Aware Service Recommendation With Enhanced Probabilistic Matrix Factorization

open access: yesIEEE Access, 2018
Owing to the ever-growing popularity of mobile computing, a large number of services have been developed for a variety of users. Considering this, recommending useful services to users is an urgent problem that needs to be addressed.
Yuyu Yin, Lu Chen, yueshen xu, Jian Wan
doaj   +1 more source

Location Aware Product Recommendations

open access: yes, 2017
Nowadays a typical retail chain store catalog encompasses thousands of products, the sheer quantity of products makes it dicult for the customer to be familiar with all the options and their specificities without spending too much time in each shopping trip.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effective Route Recommendation Leveraging Differentially Private Location Data

open access: yesMathematics
The proliferation of GPS-enabled devices and advances in positioning technologies have greatly facilitated the collection of user location data, making them valuable across various domains.
Jongwook Kim
doaj   +1 more source

Location-Aware Personalized News Recommendation With Deep Semantic Analysis

open access: yesIEEE Access, 2017
With the popularity of mobile devices and the quick growth of the mobile Web, users can now browse news wherever they want; so, their news preferences are usually related to their geographical contexts.
Cheng Chen   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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