Results 51 to 60 of about 901,086 (266)

Selecting a bus terminal location in Uşak, Turkey, using a hybrid multicriteria decision-making model

open access: yesUrbani Izziv
The location of a bus terminal is crucial for efficient urban transportation and sustainable urban mobility. The location determines visitors’ access to the city and safe, accessible, and economical transportation options.
Sümeyye Kahraman   +2 more
doaj   +1 more source

Spatial Evolution Characteristics and Influencing Factors of the Chemical Industry in Guangdong Province from an Industrial Chain Perspective

open access: yesRedai dili
Given that the chemical industry is the foundation and pillar of the national economy, explorations of its spatial evolution characteristics and influencing factors are of paramount importance for optimizing regional industrial spatial layouts and ...
Ding Shufang, Xiang Yunbo, Wang Shengyun
doaj   +1 more source

An integrated DEMATEL–IF-TOPSIS methodology for logistics centers’ location selection problem: an application for Istanbul Metropolitan area

open access: yesTransport, 2020
Logistics Centers (LCs) are among the most important facilities for rapid, cost effective, environmental friendly and secure logistics services to the urban logistics problems. Finding proper locations to LCs has an important effect on their success.
Cihan Uyanik   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Corporate location policy in the age of globalization

open access: yesJournal of Business Economics and Management, 2005
In today's economy it is very important how companies select locations for headquarters, production sites and sales offices. This paper places particular emphasis on the effects on corporate location policy resulting from a constantly proceeding ...
Andreas Palm
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Offshoring Location Decision in Fuzzy Environment

open access: yesMANAS: Journal of Engineering
Offshoring location selection is a crucial decision for firms in terms of competitiveness, flexibility, productivity, and profitability. Determining an efficient and appropriate location for offshoring has been a substantial multicriteria decision-making
Mehmet Şahin
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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