Results 71 to 80 of about 1,471 (237)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Wide-focus subject-verb inversion in Ibero-Romance: A locative account

open access: yesGlossa, 2016
This paper explores the hypothesis that wide-focus subject-verb inversion in Ibero-Romance is a type of locative inversion, involving a null locative argument.
Alice Corr
doaj   +2 more sources

L’appropriation locative

open access: yesDroit et Ville, 2006
Rozès Louis. L’appropriation locative. In: Droit et Ville, tome 61, 2006. Colloque : Qu'en est-il de la propriété ? L'appropriation en débat (Toulouse, 27-28 octobre 2005) pp. 281-296.
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Spatial Expressions In Sinhala: Appearance of Verb Forms

open access: yesKansas Working Papers in Linguistics, 1992
Most of the studies done on locative constructions in many languages show the relationship between the figure and the ground in terms of geometrical and/or topological terms.
Tilakaratne, Sunanda
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Locative as one of the most important category of Russian linguoculture

open access: yesRussian journal of linguistics: Vestnik RUDN, 2012
Locative is considered as one of the most important category of Russian linguoculture. Some locative pecularities of national and mental character in the lexical field are revealed. Locative is defined as an element of language sphere of concepts.
L N Fedoseeva
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Influence of speech situation and context on language locative expression

open access: yesRussian journal of linguistics: Vestnik RUDN, 2013
The article discusses the problem of the relationship of language expression locative semantics and speech situation, context. Defined communicative role of locative. Revealed some patterns in the sphere.
L N Fedoseeva
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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