Results 111 to 120 of about 27,703 (309)

The locative syntax of Experiencers. The case study of phraseological units as psych-predicates

open access: yesLingBaW, 2017
The name psych-verbs is commonly assigned to verbs denoting mental or emotional states, such as fear, worry, frighten, or surprise. Such verbs select a participant/an individual who experiences an emotional or mental state, usually referred to as an ...
Anna Dąbrowska
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

From location to conjunction, disjunction, partition, exemplification and association: Hebrew bein constructions

open access: yesLinguistics
Analyzing the diachrony of Hebrew bein, originally a spatial preposition ‘within/among’, this article traces several grammaticization clines associated with bein’s gradual evolution into a rich variety of functions within various constructions. While its
Bardenstein Ruti, Ariel Mira
doaj   +1 more source

Embodied memory and curatorship in children’s digital video production [PDF]

open access: yes, 2010
Digital video production in schools is often theorised, researched and written about in two ways: either as a part of media studies practice or as a technological innovation, bringing new, “creative”, digital tools into the curriculum.
Potter, John
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Possessives and spatial expressions in Spanish

open access: yesIsogloss
The aim of this paper is to analyze a type of Spanish (and Romance) complex locative non-directional prepositional expressions taking a genitive complement, like encima/cerca de (“on top/near of”). We will center our attention on an alternation that has
Olga Fernandez Soriano   +1 more
doaj   +1 more source

Preverbal negative markers in Buli [PDF]

open access: yes, 2009
This article deals with some aspects of negation in Buli, a Gur language spoken by the Bulsa people in Northern ...
Schwarz, Anne
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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