Results 121 to 130 of about 27,703 (309)

About the whereabouts of indefinites [PDF]

open access: yes, 2013
The paper characterizes three different domains in the German middle field which are relevant for the interpretation of an indefinite. It is argued that the so-called 'strong' reading of an indefinite is the basic one and that the 'weak' reading needs ...
Frey, Werner
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Linguistic and extralinguistic factors in the interpretation of children's early utterances [PDF]

open access: yes, 1975
Bestimmte seit den sechziger Jahren zur Analyse früher kindlicher Äußerungen benutzte Beschreibungsmodelle unterschätzen die sprachliche Kompetenz des Kindes, indem sie die Struktur seiner Äußerungen auf Distributionsphänomene der Oberflächenstruktur ...
Stephany, Ursula
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Voces indígenas en letras españolas: algunos aspectos morfosintácticos del contacto colonial

open access: yesLexis, 2016
In this article an approach is made to the morphosyntactic features of 9 documents that come from different archives of central Mexico; these documents show a clear interference between the Nahuatl and the Spanish languages of the XVII and XVIII ...
Mauro Alberto Mendoza Posadas
doaj  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Holger Pedersen's "Études lituaniennes" revisited [PDF]

open access: yes, 2010
Holger Pedersen’s "Études lituaniennes" reflects the issues under discussion at the time of its publication (1933). Its five unequal chapters deal with the following topics: I.
Kortlandt, Frederik H. H.
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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