Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
A 3-Year Split-Mouth Randomized Controlled Clinical Trial of Zirconia and Titanium Implant-Supported Overdentures. [PDF]
Kniha K +7 more
europepmc +1 more source
A Geometrically Transient Platform for Bioelectronic Implants
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik +13 more
wiley +1 more source
Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase +6 more
wiley +1 more source
Three-dimensional finite element analysis of two-implant-supported locator overdenture in different reinforced denture base designs under four loading conditions. [PDF]
Chen Q +6 more
europepmc +1 more source
A large‐area, deformable high‐entropy‐ceramic (HEC)‐doped triboelectric nanogenerator with a trilayer architecture is developed, consisting of an HEC‐doped triboelectric layer, a graphite‐like textile charge‐storage layer, and stretchable carbon black electrodes.
Shengyou Li +13 more
wiley +1 more source
Scapulothoracic joint function and its association with throwing-related injuries in collegiate baseball pitchers: a prospective cohort study. [PDF]
Uchida T +4 more
europepmc +1 more source
Magnetic DNA Origami Nanorotors
Magnetic actuation is a powerful and broadly applicable actuation mechanism due to its programmability and compatibility with biological entities. Here we demonstrate magnetic DNA origami nanorotors (MADONAs) by assembling magnetic nanocubes on DNA origami.
Lennart J. K. Weiß +13 more
wiley +1 more source
Finite Element Analysis of Implant-Assisted Mandibular Distal Extension Removable Partial Denture: Evaluating Stress Distribution in Premolar Versus Molar Implant Positions-An In-Silico Study. [PDF]
Bhattacharya D +6 more
europepmc +1 more source
High‐Performance Bio‐Glue From the Berries of a Parasitic Plant
We report a fully bio‐based adhesive derived primarily from a (poly)saccharide extract obtained from the berries of the hemi‐parasitic plant mistletoe (Viscum album), supplemented with tannic and malic acid without any further chemical functionalization.
Ufuk Gürer +8 more
wiley +1 more source

