Results 1 to 10 of about 1,140,452 (412)
Allele interaction--single locus genetics meets regulatory biology. [PDF]
PLoS ONE, 2010 BACKGROUND: Since the dawn of genetics, additive and dominant gene action in diploids have been defined by comparison of heterozygote and homozygote phenotypes.
Arne B Gjuvsland +3 more
doaj +9 more sources
THE LOCUS OF EVOLUTION: EVO DEVO AND THE GENETICS OF ADAPTATION [PDF]
Evolution, 2007 An important tenet of evolutionary developmental biology (“evo devo”) is that adaptive mutations affecting morphology are more likely to occur in the cis-regulatory regions than in the protein-coding regions of genes.
H. Hoekstra, J. Coyne
semanticscholar +4 more sources
Genetics of the Rh-Hr Locus in Humans [PDF]
Acta geneticae medicae et gemellologiae, 1975 An analysis is attempted to throw more light on the inheritance of rhesus factor in humans and the Fisher-Race and Wiener's concepts are respectively evaluated.It is claimed that the Rh-Hr locus is not comprised of the recombination of C, D, E, c and e genes, much less the help of the auxiliary (d) which merely appears to be a conventional approach ...
Syed Shane Raza Zaidi +2 more
openalex +4 more sources
Genetics: The MAPT locus—a genetic paradigm in disease susceptibility
Nature Reviews Neurology, 2012 Understanding how genetic variation can confer susceptibility to neurological disease is an urgent priority. A new gene-expression study has explored the relationship between DNA sequence variation at the microtubule-associated protein tau (MAPT) locus and MAPT expression in the brain, providing an exciting new paradigm for the field.
R. Wade-Martins
semanticscholar +4 more sources
SNCA locus duplication carriers: from genetics to Parkinson disease phenotypes [PDF]
Human Mutation, 2011 Genomic multiplication of the alpha‐synuclein gene (SNCA) locus is one cause of familial Parkinson disease (PD). We performed detailed genomic, SNCA expression level, clinical, neuropsychological and functional imaging analyses of a parkinsonian kindred ...
Eugénie Mutez +10 more
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Arlequin (version 3.0): An integrated software package for population genetics data analysis
Evolutionary Bioinformatics, 2005 Arlequin ver 3.0 is a software package integrating several basic and advanced methods for population genetics data analysis, like the computation of standard genetic diversity indices, the estimation of allele and haplotype frequencies, tests of ...
Laurent Excoffier +2 more
doaj +2 more sources
Genetics of the relB locus in Escherichia coli [PDF]
Journal of Bacteriology, 1977 A mutant of Escherichia coli with a delayed relaxed phenotype very similar to that of a previously described relB mutant has been obtained using a new selection procedure. The mutation giving rise to this phenotype has been shown to map at 34.5 min and to be 12% cotransducible with man. It is recessive, revertible, and most likely an allele of the relB
B Diderichsen, Niels P. Fiil, R Lavallé
openalex +4 more sources
Genetics and mapping of a new anthracnose resistance locus in Andean common bean Paloma [PDF]
BMC Genomics, 2017 Sandra Aparecida de Lima Castro +9 more
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medRxiv, 2023 Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in non-European ancestry groups in genome-wide association studies (GWAS). We constructed and analyzed a multi-ancestry GWAS dataset in the Alzheimer Disease (AD)
F. Rajabli +270 more
semanticscholar +1 more source
A genetic locus for paranoia [PDF]
Biology Letters, 2018 The psychological effects of brain-expressed imprinted genes in humans are virtually unknown. Prader–Willi syndrome (PWS) is a neurogenetic condition mediated by genomic imprinting, which involves high rates of psychosis characterized by hallucinations and paranoia, as well as autism.
Bernard Crespi +3 more
openaire +2 more sources