Results 1 to 10 of about 253,035 (314)
Allele interaction--single locus genetics meets regulatory biology. [PDF]
PLoS ONE, 2010 BACKGROUND: Since the dawn of genetics, additive and dominant gene action in diploids have been defined by comparison of heterozygote and homozygote phenotypes.
Arne B Gjuvsland +3 more
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Genetics of the Rh-Hr Locus in Humans [PDF]
Acta geneticae medicae et gemellologiae, 1975 An analysis is attempted to throw more light on the inheritance of rhesus factor in humans and the Fisher-Race and Wiener's concepts are respectively evaluated.It is claimed that the Rh-Hr locus is not comprised of the recombination of C, D, E, c and e genes, much less the help of the auxiliary (d) which merely appears to be a conventional approach ...
Sue Bebon +2 more
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Genetics of the relB locus in Escherichia coli [PDF]
Journal of Bacteriology, 1977 A mutant of Escherichia coli with a delayed relaxed phenotype very similar to that of a previously described relB mutant has been obtained using a new selection procedure. The mutation giving rise to this phenotype has been shown to map at 34.5 min and to be 12% cotransducible with man. It is recessive, revertible, and most likely an allele of the relB
N P Fiil, R Lavallé, B Diderichsen
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Development and characterization of novel microsatellite loci in the native tree frog species, Polypedates braueri and cross-species amplification in the alien species, P. megacephalus, in Taiwan [PDF]
Biodiversity Data JournalPolypedates megacephalus is an alien species first recorded in 2006 in Taiwan. The expanding population of P. megacephalus poses potential threats to the native frog species, especially to the closely-related species P. braueri.
Yuan-Cheng Cheng +2 more
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Heliyon, 2023 Background: SARS–CoV–2 virus has undergone several mutations on its genome, since the onset of the pandemic. Multiple variants of concern (VOC) have emerged including Alpha, Beta, Gamma, and Delta with the more recent one being the Omicron (B.1.1.529 ...
Michail Leventopoulos +8 more
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A genetic locus for paranoia [PDF]
Biology Letters, 2018 The psychological effects of brain-expressed imprinted genes in humans are virtually unknown. Prader–Willi syndrome (PWS) is a neurogenetic condition mediated by genomic imprinting, which involves high rates of psychosis characterized by hallucinations and paranoia, as well as autism.
Bernard Crespi +3 more
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Lack of variation at phosphoglucose isomerase (pgi) in bumblebees: implications for conservation genetics studies. [PDF]
PLoS ONE, 2013 Assessing genetic variation underlying ecologically important traits is increasingly of interest and importance in population and conservation genetics. For some groups generally useful markers exist for examining the relative role of selection and drift
Jonathan S Ellis +2 more
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Genetic Elements at the Alpha-Synuclein Locus
Frontiers in Neuroscience, 2022 Genome-wide association studies have consistently shown that the alpha-synuclein locus is significantly associated with Parkinson’s disease. The mechanism by which this locus modulates the disease pathology and etiology remains largely under-investigated.
Jordan Prahl, Gerhard A. Coetzee
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Genetic variability at the PARK16 locus [PDF]
European Journal of Human Genetics, 2010 Parkinson's disease (PD) is a complex neurodegenerative disease which is clinically heterogeneous and pathologically consists of loss of dopaminergic neurons in the substantia nigra and intracytoplasmic neuronal inclusions containing alpha-synuclein aggregations known as Lewy bodies.
Tamas Revesz +7 more
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Stem Cell Research, 2021 Prime editing uses the Cas9 nickase fused to a reverse transcriptase to copy a DNA sequence into a specific locus from a ‘prime editing’ guide RNA (pegRNA), eliminating the need for double-stranded DNA breaks and donor DNA templates.
Nike Bharucha +3 more
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