Results 1 to 10 of about 1,170,009 (287)
Allele interaction--single locus genetics meets regulatory biology. [PDF]
PLoS ONE, 2010 BACKGROUND: Since the dawn of genetics, additive and dominant gene action in diploids have been defined by comparison of heterozygote and homozygote phenotypes.
Arne B Gjuvsland +3 more
doaj +4 more sources
Genetics and mapping of a new anthracnose resistance locus in Andean common bean Paloma [PDF]
BMC Genomics, 2017 BackgroundThe Andean cultivar Paloma is resistant to Mesoamerican and Andean races of Colletotrichum lindemuthianum, the fungal pathogen that causes the destructive anthracnose disease in common bean. Remarkably, Paloma is resistant to Mesoamerican races
Sandra Aparecida de Lima Castro +9 more
openalex +2 more sources
Editorial: the applications of new multi-locus GWAS methodologies in the genetic dissection of complex traits [PDF]
Frontiers in Plant Science, 2019 Since the establishment of the mixed linear model (MLM) method for genome-wide association studies (GWAS) by Zhang et al. (2005) and Yu et al. (2006), a series of new MLM-based methods have been proposed (Feng et al., 2016).
Dunwell, Jim M. +2 more
core +3 more sources
Arlequin (version 3.0): An integrated software package for population genetics data analysis
Evolutionary Bioinformatics, 2005 Arlequin ver 3.0 is a software package integrating several basic and advanced methods for population genetics data analysis, like the computation of standard genetic diversity indices, the estimation of allele and haplotype frequencies, tests of ...
Laurent Excoffier +2 more
doaj +2 more sources
SNCA locus duplication carriers: from genetics to Parkinson disease phenotypes [PDF]
Human Mutation, 2011 Genomic multiplication of the alpha‐synuclein gene (SNCA) locus is one cause of familial Parkinson disease (PD). We performed detailed genomic, SNCA expression level, clinical, neuropsychological and functional imaging analyses of a parkinsonian kindred ...
Eugénie Mutez +10 more
openalex +2 more sources
Heliyon, 2023 Background: SARS–CoV–2 virus has undergone several mutations on its genome, since the onset of the pandemic. Multiple variants of concern (VOC) have emerged including Alpha, Beta, Gamma, and Delta with the more recent one being the Omicron (B.1.1.529 ...
Michail Leventopoulos +8 more
doaj +1 more source
Plasma proteomic associations with genetics and health in the UK Biobank
Nature, 2023 The Pharma Proteomics Project generates the largest open-access plasma proteomics dataset to date, offering insights into trans protein quantitative trait loci across multiple biological domains, and highlighting genetic influences on ligand–receptor ...
B. Sun +55 more
semanticscholar +1 more source
The population genetics characteristics of a 90 locus panel of microhaplotypes
Human Genetics, 2021 Single-nucleotide polymorphisms (SNPs) and small genomic regions with multiple SNPs (microhaplotypes, MHs) are rapidly emerging as novel forensic investigative tools to assist in individual identification, kinship analyses, ancestry inference, and ...
A. Pakstis +5 more
semanticscholar +1 more source
Nature Immunology, 2023 Here the authors identify genetic effectors of the level of inflammation-related plasma proteins and use Mendelian randomization to identify proteins that contribute to immune-mediated disease risk.
Jinghua Zhao +40 more
semanticscholar +1 more source
Lack of variation at phosphoglucose isomerase (pgi) in bumblebees: implications for conservation genetics studies. [PDF]
PLoS ONE, 2013 Assessing genetic variation underlying ecologically important traits is increasingly of interest and importance in population and conservation genetics. For some groups generally useful markers exist for examining the relative role of selection and drift
Jonathan S Ellis +2 more
doaj +1 more source