Results 101 to 110 of about 1,170,009 (287)
Genetics of Phenylketonuria: Then and Now
Human Mutation, 2016 More than 950 phenylalanine hydroxylase (PAH) gene variants have been identified in people with phenylketonuria (PKU). These vary in their consequences for the residual level of PAH activity, from having little or no effect to abolishing PAH activity ...N. Blausemanticscholar +1 more sourceGenetic analysis of the flaA locus of Bacillus subtilis
Journal of Bacteriology, 1991 We isolated two clones of recombinant lambda bacteriophage with overlapping inserts of Bacillus subtilis chromosomal DNA corresponding to part of the flaA locus. The flaA4 and flaA15 mutations were localized on the physical map by marker rescue experiments.HAUSER PM, CRABB WD, FIORA MG, SCOFFONE F, GALIZZI, ALESSANDRO +4 moreopenaire +4 more sourcesMulti-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK, GRB14, and KIAA0825 as novel risk loci for Alzheimer disease: the Alzheimer Disease Genetics Consortium
medRxiv, 2023 F. Rajabli, Penelope H. Benchek, G. Tosto, Nicholas A. Kushch, Jin Sha, Katrina Bazemore, Congcong Zhu, Wan-Ping Lee, Jacob Haut, K. Hamilton-Nelson, Nicholas R. Wheeler, Yi Zhao, John J Farrell, M. Grunin, Y. Leung, Pavel P. Kuksa, Donghe Li, Eder Lucio da Fonseca, Jesse Mez, Ellen L Palmer, Jagan A. Pillai, R. Sherva, Yeunjoo E. Song, Xiaoling Zhang, T. Iqbal, Omkar Pathak, O. Valladares, A. Kuzma, E. Abner, P. Adams, Alyssa Aguirre, Marilyn S. Albert, R. Albin, M. Allen, Lisa Alvarez, L. Apostolova, Steven E. Arnold, Sanjay Asthana, Craig S. Atwood, Gayle Ayres, Clinton T. Baldwin, Robert C. Barber, Lisa L. Barnes, S. Barral, T. Beach, James T. Becker, Gary W Beecham, D. Beekly, B. Benitez, David A. Bennett, J. Bertelson, Thomas D. Bird, Deborah Blacker, B. Boeve, J. Bowen, A. Boxer, J. Brewer, James R. Burke, Jeffrey M. Burns, J. Buxbaum, Nigel J. Cairns, L. Cantwell, Chuanhai Cao, Christopher S. Carlson, C. Carlsson, R. Carney, M. Carrasquillo, S. Chasse, M. Chesselet, N. Chin, H. Chui, Jaeyoon Chung, Suzanne Craft, Paul K. Crane, D. Cribbs, E. Crocco, C. Cruchaga, M. Cuccaro, M. Cullum, E. Darby, Barbara Davis, P. D. De Jager, C. DeCarli, J. Detoledo, M. Dick, Dennis W. Dickson, B. Dombroski, Rachelle S. Doody, R. Duara, Nilufer Ertekin-Taner, Denis A. Evans, K. Faber, T. Fairchild, K. Fallon, D. Fardo, Marty Farlow, Victoria Fernandez-Hernandez, S. Ferris, T. Foroud, Matthew P. Frosch, B. Fulton-Howard, D. Galasko, Adriana Gamboa, M. Gearing, D. Geschwind, B. Ghetti, John R. Gilbert, A. Goate, T. Grabowski, N. Graff-Radford, R. Green, J. Growdon, H. Hakonarson, James R. Hall, R. Hamilton, O. Harari, John Hardy, L. Harrell, Elizabeth Head, Victor Henderson, Michelle Hernandez, T. Hohman, Lawrence S Honig, R. Huebinger, M. Huentelman, Christine M. Hulette, Bradley T. Hyman, L. Hynan, L. Ibañez, Gail P. Jarvik, S. Jayadev, Lee‐Way Jin, Kim Johnson, Leigh Johnson, M. Kamboh, A. Karydas, M. Katz, J. Kauwe, Jeffrey A. Kaye, C. Keene, Aisha Khaleeq, Ronald Kim, Janice Knebl, Neil W. Kowall, Joel H Kramer, W. Kukull, Frank LaFerla, J. Lah, Eric B. Larson, Alan J. Lerner, James B. Leverenz, A. Levey, Andrew P. Lieberman, Richard B. Lipton, Mark A Logue, Oscar L. Lopez, Kathryn L. Lunetta, Constantine G. Lyketsos, Douglas Mains, Flanagan E. Margaret, D. C. Marson, Eden R. Martin, F. Martiniuk, D. Mash, E. Masliah, P. Massman, Arjun V. Masurkar, W. McCormick, S. McCurry, Andrew N McDavid, Stefan McDonough, Ann C Mckee, M. Mesulam, Bruce L. Miller, C. Miller, Joshua W. Miller, Thomas J. Montine, E. Monuki, John C. Morris, S. Mukherjee, Amanda J. Myers, Trung Nguyen, Sid E. O'Bryant, J. Olichney, Marcia G. Ory, Raymond Palmer, Joseph E. Parisi, Henry L Paulson, V. Pavlik, D. Paydarfar, Victoria Perez, Elaine Peskind, Ronald C. Petersen, A. Pierce, Marsha S Polk, Wayne W. Poon, Huntington Potter, L. Qu, M. Quiceno, Joseph F. Quinn, A. Raj, Murray M. Raskind, E. Reiman, B. Reisberg, Joan S. Reisch, J. Ringman, Erik D. Roberson, Monica Rodriguear, E. Rogaeva, H. Rosen, Roger N. Rosenberg, D. Royall, M. Sager, Mary Sano, A. Saykin, Julie A Schneider, Lon S. Schneider, W. Seeley, S. Slifer, Scott Small, Amanda G. Smith, Janet Smith, J. Sonnen, S. Spina, Peter St George-Hyslop, Robert A. Stern, Alan B Stevens, Stephen Strittmatter, David Sultzer, Russell H Swerdlow, Rudolph E Tanzi, J. Tilson, J. Trojanowski, Juan C. Troncoso, D. Tsuang, V. V. Van Deerlin, Linda J. van Eldik, Jeffery M Vance, B. Vardarajan, R. Vassar, H. Vinters, J. Vonsattel, Sandra Weintraub, K. Welsh-Bohmer, Patrice L. Whitehead, Ellen M. Wijsman, Kirk C. Wilhelmsen, Benjamin Williams, J. Williamson, Henrik Wilms, T. Wingo, Thomas Wisniewski, R. Woltjer, Martin Woon, Clinton B. Wright, chuang-Kuo Wu, Steven G. Younkin, chang-en Yu, Lei Yu, Xiongwei Zhu, B. Kunkle, William S Bush, Li-San Wang, Lindsay A Farrer, J. Haines, Richard Mayeux, M. Pericak-Vance, G. Schellenberg, G. Jun, C. Reitz, A. Naj +270 moresemanticscholar +1 more sourceRate of adaptation in sexuals and asexuals: A solvable model of the
Fisher-Muller effect
, 2013 The adaptation of large asexual populations is hampered by the competition
between independently arising beneficial mutations in different individuals,
which is known as clonal interference.Bürger, Felsenstein, Franke, Gillespie, Joachim Krug, Kimura, Kondrashov, Kondrashov, Su-Chan Park, Turner, Wright +10 morecore +1 more sourceDiscovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium
PLoS Genetics, 2017 Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for BMI, WHRadjBMI), but few have been identified through screening of the African ...M. Ng, M. Graff, Yingchang Lu, A. Justice, Poorva Mudgal, Ching‐Ti Liu, K. Young, L. Yanek, M. Feitosa, M. Wojczynski, K. Rand, Jennifer A. Brody, B. Cade, B. Cade, Latchezar Dimitrov, Qing Duan, Xiuqing Guo, L. Lange, M. Nalls, H. Okut, S. Tajuddin, B. Tayo, S. Vedantam, S. Vedantam, J. Bradfield, Guanjie Chen, Wei-Min Chen, A. Chesi, M. Irvin, Badri K. Padhukasahasram, Jennifer A. Smith, W. Zheng, M. Allison, C. Ambrosone, E. Bandera, Traci M. Bartz, S. Berndt, L. Bernstein, W. Blot, E. Bottinger, J. Carpten, S. Chanock, Y. Chen, D. Conti, R. Cooper, M. Fornage, B. Freedman, M. Garcia, P. Goodman, Yu-Han H. Hsu, Yu-Han H. Hsu, Yu-Han H. Hsu, Jennifer J. Hu, C. Huff, S. Ingles, E. John, E. John, R. Kittles, E. Klein, Jin Li, B. McKnight, Uma Nayak, B. Nemesure, A. Ogunniyi, A. Olshan, M. Press, Rebecca R. Rohde, B. Rybicki, B. Salako, M. Sanderson, Y. Shao, D. Siscovick, J. Stanford, J. Stanford, V. Stevens, Alexander Stram, S. Strom, Dhananjay Vaidya, Dhananjay Vaidya, J. Witte, Jie Yao, Xiaofeng Zhu, R. Ziegler, A. Zonderman, A. Adeyemo, S. Ambs, M. Cushman, J. Faul, H. Hakonarson, H. Hakonarson, A. Levin, K. Nathanson, E. Ware, D. Weir, Wei Zhao, Degui Zhi, D. Arnett, S. Grant, S. Kardia, Olufunmilayo I Oloapde, D. Rao, C. Rotimi, M. Sale, L. Williams, B. Zemel, B. Zemel, D. Becker, I. Borecki, I. Borecki, M. Evans, T. Harris, J. Hirschhorn, J. Hirschhorn, J. Hirschhorn, Yun Li, Sanjay R. Patel, B. Psaty, B. Psaty, J. Rotter, James G. Wilson, D. Bowden, L. Cupples, L. Cupples, C. Haiman, R. Loos, K. North +125 moresemanticscholar +1 more sourceOmics data reveal the unusual asexual-fruiting nature and secondary metabolic potentials of the medicinal fungus Cordyceps cicadae
BMC Genomics, 2017 Background Ascomycete Cordyceps species have been using as valued traditional Chinese medicines. Particularly, the fruiting bodies of Cordyceps cicadae (syn. Isaria cicadae) have long been utilized for the treatment of chronic kidney disease.Yuzhen Lu, Feifei Luo, Kai Cen, Guohua Xiao, Ying Yin, Chunru Li, Zengzhi Li, Shuai Zhan, Huizhan Zhang, Chengshu Wang +9 moredoaj +1 more sourceThe Genetics of Pemphigus Vulgaris
Frontiers in Medicine, 2018 Pemphigus vulgaris (PV) is a severe autoimmune blistering disease caused by auto-antibodies (auto-Abs) directed against epithelial desmosomal components and leading to disruption of cell-cell adhesion.D. Vodo, O. Sarig, E. Sprechersemanticscholar +1 more source
