Results 111 to 120 of about 540,367 (350)
Reinforcement of genetic coherence: a single-locus model
Biosystems, 1997 Genetic coherence and genetic separation are the outcome of evolutionary mechanisms which maintain genetic variation within populations through recombination on the one hand, and which divide this variation via speciation between reproductively (recombinatorically) more or less isolated populations on the other.
Steiner, Wilfried, Gregorius, Hans-Rolf
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Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta PraktikiIn modern forensic practice, molecular genetic studies play an extremely important role, especially in wartime. DNA identification allows you to identify a person by traces of biological origin, which has become critically important for the ...
L. I. Kucherenko +3 more
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A review on SNP and other types of molecular markers and their use in animal genetics
Genetics Selection Evolution, 2002 During the last ten years, the use of molecular markers, revealing polymorphism at the DNA level, has been playing an increasing part in animal genetics studies. Amongst others, the microsatellite DNA marker has been the most widely used, due to its easy
Eggen André +3 more
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Applications in Plant Sciences, 2013 Premise of the study: Spartina alterniflora is one of the nine most notoriously invasive plants in China. Microsatellite markers were developed for this species to investigate its invasiveness and genetic diversity.
Wuxia Guo +5 more
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Computing power of quantitative trait locus association mapping for haploid loci
BMC Bioinformatics, 2009 Background Statistical power calculations are a critical part of any study design for gene mapping. Most calculations assume that the locus of interest is biallelic.
Gordon Derek, Zinn Andrew R
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Molecular genetics of the brown (b)-locus region of mouse chromosome 4. I. Origin and molecular mapping of radiation- and chemical-induced lethal brown deletions. [PDF]
, 1994 Eugene M. Rinchik +5 more
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Genetic evaluation with finite locus models
, 2018 The availability of genotypic data in recent years has resulted in increased interest in the use of marker assisted genetic evaluation (MAGE) in livestock species. Under additive inheritance, Henderson's mixed model equations (HMME) provide an efficient approach to obtain genetic evaluations by marker assisted best linear unbiased prediction (MABLUP ...
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