Results 151 to 160 of about 260,346 (338)
Molecular population genetics of the alcohol dehydrogenase locus in the Hawaiian drosophilid D. mimica [PDF]
, 1996 F J Ayala, Colin Campbell, R K Selander
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Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
Information Theory and Population Genetics [PDF]
arXiv, 2011 The key findings of classical population genetics are derived using a framework based on information theory using the entropies of the allele frequency distribution as a basis. The common results for drift, mutation, selection, and gene flow will be rewritten both in terms of information theoretic measurements and used to draw the classic conclusions ...
arxiv
Genetics of a New Male-Sterility Locus in Pigeonpea (Cajanus cajan [L.] Millsp.) [PDF]
, 2001 K B Saxena
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Population genetics characteristics of a 90 locus panel of microhaplotypes
, 2021 A.J. Pakstis +5 more
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Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
مجله دانشگاه علوم پزشکی بیرجند, 2018 Background and Aim: Short tandem repeat (STR) markers, are conserved region in human genome and highly polymorphic between individuals. Nowadays, genotyping of STR marker is widely known and used for the genetic identification of individuals in forensic ...
Mohammadreza Nassiri +6 more
doaj
The gene's eye-view of quantitative genetics [PDF]
arXivModelling the evolution of a continuous trait in a biological population is one of the oldest problems in evolutionary biology, which led to the birth of quantitative genetics. With the recent development of GWAS methods, it has become essential to link the evolution of the trait distribution to the underlying evolution of allelic frequencies at many ...
arxiv
Quantitative Trait Locus Mapping Based on Resampling in a Vast Maize Testcross Experiment and Its Relevance to Quantitative Genetics for Complex Traits [PDF]
, 2004 Chris‐Carolin Schön +5 more
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Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source