Results 11 to 20 of about 1,170,009 (287)
Genetics of the Rh-Hr Locus in Humans [PDF]
Acta geneticae medicae et gemellologiae, 1975 An analysis is attempted to throw more light on the inheritance of rhesus factor in humans and the Fisher-Race and Wiener's concepts are respectively evaluated.It is claimed that the Rh-Hr locus is not comprised of the recombination of C, D, E, c and e genes, much less the help of the auxiliary (d) which merely appears to be a conventional approach ...
Syed Shane Raza Zaidi +2 more
openalex +4 more sources
A genetic locus for paranoia [PDF]
Biology Letters, 2018 The psychological effects of brain-expressed imprinted genes in humans are virtually unknown. Prader–Willi syndrome (PWS) is a neurogenetic condition mediated by genomic imprinting, which involves high rates of psychosis characterized by hallucinations and paranoia, as well as autism.
Bernard Crespi +3 more
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Genetic Elements at the Alpha-Synuclein Locus
Frontiers in Neuroscience, 2022 Genome-wide association studies have consistently shown that the alpha-synuclein locus is significantly associated with Parkinson’s disease. The mechanism by which this locus modulates the disease pathology and etiology remains largely under-investigated.
Jordan Prahl, Gerhard A. Coetzee
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Genetic variability at the PARK16 locus [PDF]
European Journal of Human Genetics, 2010 Parkinson's disease (PD) is a complex neurodegenerative disease which is clinically heterogeneous and pathologically consists of loss of dopaminergic neurons in the substantia nigra and intracytoplasmic neuronal inclusions containing alpha-synuclein aggregations known as Lewy bodies.
Tamas Revesz +7 more
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Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire
Nature Communications, 2023 Variation in the antibody response has been linked to differential outcomes in disease, and suboptimal vaccine and therapeutic responsiveness, the determinants of which have not been fully elucidated.
O. Rodriguez +12 more
semanticscholar +1 more source
Stem Cell Research, 2021 Prime editing uses the Cas9 nickase fused to a reverse transcriptase to copy a DNA sequence into a specific locus from a ‘prime editing’ guide RNA (pegRNA), eliminating the need for double-stranded DNA breaks and donor DNA templates.
Nike Bharucha +3 more
doaj +1 more source
Genetic Imprinting: Conflict at the Callipyge Locus [PDF]
Current Biology, 2005 The imprinted Dlk1-Gtl2 region of the mammalian genome - which in sheep encompasses the Callipyge locus, known for its unusual mode of inheritance - encodes a number of maternally expressed miRNAs. Five of these miRNAs, hosted by the antisense transcript antiPeg11, have now been shown to target degradation of the paternally expressed Peg11 mRNA by an ...
Annabelle Lewis, Lisa Redrup
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The Gene Encoding Dihydroflavonol 4-Reductase Is a Candidate for the anthocyaninless Locus of Rapid Cycling Brassica rapa (Fast Plants Type). [PDF]
PLoS ONE, 2016 Rapid cycling Brassica rapa, also known as Wisconsin Fast Plants, are a widely used organism in both K-12 and college science education. They are an excellent system for genetics laboratory instruction because it is very easy to conduct genetic crosses ...
Douglas L Wendell +2 more
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Genetics of rheumatoid arthritis
Seminars in Immunopathology, 2022 Rheumatoid arthritis (RA) is an inflammatory autoimmune disease involving symmetric joints and is generally characterized by persistent pain, tenderness, and destruction of joints.
L. Padyukov
semanticscholar +1 more source
Scientific Reports, 2022 Genome-wide association studies (GWAS) have identified many common variant loci associated with asthma susceptibility, but few studies investigate the genetics underlying moderate-to-severe asthma risk.
Diana Chang +23 more
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