RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Advanced Biology, EarlyView.Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav +5 more
wiley +1 more source
Targeted Forward Genetics: Saturating Mutational Analyses of Specific Target Loci Within the Genome. [PDF]
Methods Mol BiolProtacio RU, Wahls WP.
europepmc +1 more source
Systems genetics approach uncovers associations between host amylase locus, gut microbiome and metabolic traits in hyperlipidemic mice [PDF]
Qijun Zhang +7 more
openalex +1 more source
Toward Design Principles for Biomolecular Condensates for Metabolic Pathways
Advanced Biology, EarlyView.Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André +3 more
wiley +1 more source
Genetic Diversity and Ethnic Tapestry of Kazakhstan as Inferred from HLA Polymorphism and Population Dynamics: A Comprehensive Review. [PDF]
Genes (Basel)Turganbekova A +3 more
europepmc +1 more source
THE GENETICS OF A MUTABLE GENE AT THE WHITE LOCUS OF DROSOPHILA MELANOGASTER
, 1967 M M Green
openalex +2 more sources
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Evolutionary lineage-specific genomic imprinting at the ZNF791 locus. [PDF]
PLoS GenetAhn J +7 more
europepmc +1 more source
GENETICS OF SORDARIA FIMICOLA. VI. GENE CONVERSION AT THE g LOCUS IN MUTANT x WILD TYPE CROSSES
, 1967 Y. Kitani, Lindsay S. Olive
openalex +2 more sources
ADAM-multi: software to simulate complex breeding programs for animals and plants with different ploidy levels and generalized genotypic effect models to account for multiple alleles. [PDF]
Front GenetChu TT, Jensen J.
europepmc +1 more source