Results 21 to 30 of about 253,035 (314)

Adaptive topographies and equilibrium selection in an evolutionary game. [PDF]

open access: yesPLoS ONE, 2015
It has long been known in the field of population genetics that adaptive topographies, in which population equilibria maximise mean population fitness for a trait regardless of its genetic bases, do not exist.
Hinke M Osinga, James A R Marshall
doaj   +1 more source

lociNGS: a lightweight alternative for assessing suitability of next-generation loci for evolutionary analysis. [PDF]

open access: yesPLoS ONE, 2012
Genomic enrichment methods and next-generation sequencing produce uneven coverage for the portions of the genome (the loci) they target; this information is essential for ascertaining the suitability of each locus for further analysis.
Sarah M Hird
doaj   +1 more source

Genetic Analysis of Mitochondrial Sorting from the MSC3 Mosaic Mutant of Cucumber

open access: yesJournal of the American Society for Horticultural Science, 2021
Cucumber (Cucumis sativus) plants regenerated from cell cultures occasionally possess mosaic (MSC) phenotypes on cotyledons and leaves. Lines MSC3 and MSC16 have distinct MSC phenotypes and originated from plants regenerated from different cell-culture ...
Lyle T. Wallace, Michael J. Havey
doaj   +1 more source

Mutation analysis of 21 autosomal short tandem repeats in Han population from Hunan, China

open access: yesAnnals of Human Biology, 2019
Background: Short tandem repeats (STRs) are powerful genetic markers widely used in human genetics. Population data and locus-specific mutation rates of STRs are crucial for the evaluation and interpretation of genetic evidence in forensic and population
Wei Xu   +7 more
doaj   +1 more source

Using Gene Editing to Establish a Safeguard System for Pluripotent Stem-Cell-Based Therapies

open access: yesiScience, 2019
Summary: A major challenge in using human pluripotent stem cells (hPSCs) in therapy is the risk of teratoma formation due to contaminating undifferentiated stem cells. We used CRISPR-Cas9 for in-frame insertion of a suicide gene, iC9, into the endogenous
Youjun Wu   +5 more
doaj   +1 more source

GENETIC CHANGE IN MUTATIONS AT THE T/t-LOCUS IN THE MOUSE [PDF]

open access: yesGenetics, 1976
ABSTRACT Recessive lethal or semilethal alleles at the T/t locus in the mouse generate new t-variants, with characteristics different from the parent allele at a rate of about 10-3. Almost invariably the variant chromosome carries marker genes derived from the opposite parental chromosome.
Bennett, D, Dunn, L C, Artzt, K
openaire   +2 more sources

Using bioinformatics and systems genetics to dissect HDL-cholesterol genetics in an MRL/MpJ × SM/J intercross[S]

open access: yesJournal of Lipid Research, 2012
A higher incidence of coronary artery disease is associated with a lower level of HDL-cholesterol. We searched for genetic loci influencing HDL-cholesterol in F2 mice from a cross between MRL/MpJ and SM/J mice.
Magalie S. Leduc   +6 more
doaj   +1 more source

Irradiation induced inversions suppress recombination between the M locus and morphological markers in Aedes aegypti

open access: yesBMC Genetics, 2020
Background Aedes aegypti is the primary vector of arthropod-borne viruses and one of the most widespread and invasive mosquito species. Due to the lack of efficient specific drugs or vaccination strategies, vector population control methods, such as the ...
Antonios A. Augustinos   +5 more
doaj   +1 more source

Analisis Keanekaragaman Genetik dan Diferensiasi Jati Jawa dan Madura berdasarkan Marka Mikrosatelit untuk Mendukung Fingerprinting Jati

open access: yesBiosaintifika: Journal of Biology & Biology Education, 2010
Analysis fingerprinting teak is supported by information about teak’s character molecularly. The information is gotten by analyzing 3 primary microsatellite in 46 teak samples that produce total 18 kinds of alel averagely 6 alel per locus.
Munisyatul Millah   +2 more
doaj   +1 more source

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