Results 21 to 30 of about 1,170,009 (287)

Genetics of the relB locus in Escherichia coli [PDF]

open access: bronzeJournal of Bacteriology, 1977
A mutant of Escherichia coli with a delayed relaxed phenotype very similar to that of a previously described relB mutant has been obtained using a new selection procedure. The mutation giving rise to this phenotype has been shown to map at 34.5 min and to be 12% cotransducible with man. It is recessive, revertible, and most likely an allele of the relB
B Diderichsen, Niels P. Fiil, R Lavallé
openalex   +4 more sources

Genetics of amyotrophic lateral sclerosis: seeking therapeutic targets in the era of gene therapy

open access: yesJournal of Human Genetics, 2022
Amyotrophic lateral sclerosis (ALS) is an intractable disease that causes respiratory failure leading to mortality. The main locus of ALS is motor neurons.
N. Suzuki   +3 more
semanticscholar   +1 more source

Development and characterization of 16 novel microsatellite markers by Transcriptome sequencing for Angelica dahurica and test for cross-species amplification

open access: yesBMC Plant Biology, 2020
Background Angelica dahurica (Apiaceae) is an important herb in traditional Chinese medicine. Because of its important medicinal and economic values, its wild resources were over-exploited and increasingly reduced.
Qianqian Liu   +7 more
doaj   +1 more source

An X-STRs analysis of the Iraqi Sorani Kurds.

open access: yesPLoS ONE, 2023
A database for the Iraqi Sorani Kurds, specifically focused on the 12 X-short tandem repeat (STR) loci, has been developed to fascilitate forensic and population genetics investigations.
Balnd M Albarzinji   +5 more
doaj   +1 more source

A molecular quantitative trait locus map for osteoarthritis

open access: yesNature Communications, 2021
Osteoarthritis causes pain and functional disability for over 500 million people worldwide. To develop disease-stratifying tools and modifying therapies, we need a better understanding of the molecular basis of the disease in relevant tissue and cell ...
J. Steinberg   +15 more
semanticscholar   +1 more source

Increasing power for voxel-wise genome-wide association studies : the random field theory, least square kernel machines and fast permutation procedures [PDF]

open access: yes, 2012
Imaging traits are thought to have more direct links to genetic variation than diagnostic measures based on cognitive or clinical assessments and provide a powerful substrate to examine the influence of genetics on human brains. Although imaging genetics
Feng, Jianfeng   +4 more
core   +1 more source

Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient [PDF]

open access: yes, 2012
Peer reviewedPublisher ...
Andreatta, Matthew   +6 more
core   +8 more sources

Deletion of the Alzheimer’s disease risk gene Abi3 locus results in obesity and systemic metabolic disruption in mice

open access: yesFrontiers in Aging Neuroscience, 2022
Alzheimer’s disease (AD) genetics studies have identified a coding variant within ABI3 gene that increases the risk of developing AD. Recently, we demonstrated that deletion of the Abi3 gene locus dramatically exacerbates AD neuropathology in a ...
Daniel C. Smith   +16 more
doaj   +1 more source

Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans [PDF]

open access: yes, 2017
Compelling evidence for the inherited nature of essential hypertension has led to extensive research in rats and humans. Rats have served as the primary model for research on the genetics of hypertension resulting in identification of genomic regions ...
Allbutt TC   +34 more
core   +1 more source

The effect of recurrent mutations on genetic diversity in a large population of varying size [PDF]

open access: yes, 2016
Recurrent mutations are a common phenomenon in population genetics. They may be at the origin of the fixation of a new genotype, if they give a phenotypic advantage to the carriers of the new mutation.
Smadi, Charline
core   +3 more sources

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