Genetics of the relB locus in Escherichia coli [PDF]
A mutant of Escherichia coli with a delayed relaxed phenotype very similar to that of a previously described relB mutant has been obtained using a new selection procedure. The mutation giving rise to this phenotype has been shown to map at 34.5 min and to be 12% cotransducible with man. It is recessive, revertible, and most likely an allele of the relB
B Diderichsen, Niels P. Fiil, R Lavallé
openalex +4 more sources
Genetics of amyotrophic lateral sclerosis: seeking therapeutic targets in the era of gene therapy
Amyotrophic lateral sclerosis (ALS) is an intractable disease that causes respiratory failure leading to mortality. The main locus of ALS is motor neurons.
N. Suzuki+3 more
semanticscholar +1 more source
Background Angelica dahurica (Apiaceae) is an important herb in traditional Chinese medicine. Because of its important medicinal and economic values, its wild resources were over-exploited and increasingly reduced.
Qianqian Liu+7 more
doaj +1 more source
An X-STRs analysis of the Iraqi Sorani Kurds.
A database for the Iraqi Sorani Kurds, specifically focused on the 12 X-short tandem repeat (STR) loci, has been developed to fascilitate forensic and population genetics investigations.
Balnd M Albarzinji+5 more
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A molecular quantitative trait locus map for osteoarthritis
Osteoarthritis causes pain and functional disability for over 500 million people worldwide. To develop disease-stratifying tools and modifying therapies, we need a better understanding of the molecular basis of the disease in relevant tissue and cell ...
J. Steinberg+15 more
semanticscholar +1 more source
Increasing power for voxel-wise genome-wide association studies : the random field theory, least square kernel machines and fast permutation procedures [PDF]
Imaging traits are thought to have more direct links to genetic variation than diagnostic measures based on cognitive or clinical assessments and provide a powerful substrate to examine the influence of genetics on human brains. Although imaging genetics
Feng, Jianfeng+4 more
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Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient [PDF]
Peer reviewedPublisher ...
Andreatta, Matthew+6 more
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Alzheimer’s disease (AD) genetics studies have identified a coding variant within ABI3 gene that increases the risk of developing AD. Recently, we demonstrated that deletion of the Abi3 gene locus dramatically exacerbates AD neuropathology in a ...
Daniel C. Smith+16 more
doaj +1 more source
Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans [PDF]
Compelling evidence for the inherited nature of essential hypertension has led to extensive research in rats and humans. Rats have served as the primary model for research on the genetics of hypertension resulting in identification of genomic regions ...
Allbutt TC+34 more
core +1 more source
The effect of recurrent mutations on genetic diversity in a large population of varying size [PDF]
Recurrent mutations are a common phenomenon in population genetics. They may be at the origin of the fixation of a new genotype, if they give a phenotypic advantage to the carriers of the new mutation.
Smadi, Charline
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