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Identification of novel genes responsible for a pollen killer present in local natural populations of Arabidopsis thaliana. [PDF]
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Genetic characterization of the Dyscalc locus
Mammalian Genome, 2002Calcification occurs frequently in the development of atherosclerotic lesions, and studies in mice have indicated a genetic contribution. We now show that one genetic factor contributing to aortic calcification is the Dyscalc locus, previously shown to contribute to myocardial calcification. Thus, the Dyscalc locus, on proximal mouse Chromosome (Chr) 7,
Kelly L. Krass +5 more
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Genetic characterization of the polycotyledon locus in tomato
Theoretical and Applied Genetics, 2006Developmental mutants serve as a useful material to unravel the mechanisms necessary for organ development. The polycotyledon (poc) mutant of tomato, with multiple cotyledons in the seedling and varied phenotypic effects in the adult plant is one such mutant.
Rameshwar Sharma +5 more
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Journal of Experimental Zoology, 1987
AbstractTyrosinase activities and dopachrome conversion activity were evaluated in extracts made from skins of 6‐day‐old mice that were mutant at the agouti and albino loci. Dopa oxidase (DO) activity of tyrosinase in fully pigmented (C/C) mice is reduced in extracts made from skins of yellow 6‐day‐old mice as compared to those of black mice ...
Phil Pendergast, M. Lynn Lamoreux
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AbstractTyrosinase activities and dopachrome conversion activity were evaluated in extracts made from skins of 6‐day‐old mice that were mutant at the agouti and albino loci. Dopa oxidase (DO) activity of tyrosinase in fully pigmented (C/C) mice is reduced in extracts made from skins of yellow 6‐day‐old mice as compared to those of black mice ...
Phil Pendergast, M. Lynn Lamoreux
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Genetics of Minute Locus in Drosophila Melanogaster
1980Minutes are a class of dominant mutants that are characterized by their recessive lethality, increased developmental time, smaller body with short fine bristles in the heterozygotes and with varying degrees of reduced survival and fertility (Lindsley et al., 1972).
David L. Shellenbarger +1 more
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Molecular and Genetic Analyses at the CF Locus
1991Cystic fibrosis (CF) is the most frequent lethal autosomal recessive disorder of Caucasian populations. The disease incidence is commonly quoted as 1 in 2500 (Boat et al., 1989), but varies widely in different populations. Frequencies as low as 1:90,000 exist (Wright and Morton, 1968), and as high as 1:377 in Brittany (Bois et al., 1978), 1:313 in the ...
P. Stanislovitis +3 more
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Somatic and germline genetics at the JAK2 locus
Nature Genetics, 2009Myeloproliferative neoplasms are hematological malignancies frequently associated with somatically acquired mutation of the JAK2 gene. A new study shows that these mutations are preferentially found within a particular inherited JAK2 haplotype, implying the existence of a strong, but uncharacterized, interaction between somatic and germline genetics at
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