Results 311 to 320 of about 540,367 (350)

Sam Karlin and multi-locus population genetics

Theoretical Population Biology, 2009
Between 1967 and 1982, Sam Karlin made fundamental contributions to many areas of deterministic population genetic theory. This remembrance focuses on his work in multi-locus population genetics, primarily on the interaction between genotypic selection and the rate of recombination.
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Genetic characterization of the polycotyledon locus in tomato

Theoretical and Applied Genetics, 2006
Developmental mutants serve as a useful material to unravel the mechanisms necessary for organ development. The polycotyledon (poc) mutant of tomato, with multiple cotyledons in the seedling and varied phenotypic effects in the adult plant is one such mutant.
Kavitha, Madishetty, P, Bauer, M S, Sharada, A S A, Al-Hammadi, R, Sharma   +4 more
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Worldwide genetic diversity at the HLA-DQA1 locus

American Journal of Human Biology, 1997
Genotype, gene, or phenotype frequency data, obtained by PCR analysis with sequence specific oligonucleotide probes at the HLA-DQA1 locus, in 176 population samples, each consisting of 30 or more individuals, from all around the world were analyzed. The sampled populations were assigned to the following nine groups: African, Afro-American, American ...
F, Rivas, Y, Zhong, N, Olivares, R M, Cerda-Flores, R, Chakraborty   +4 more
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Simplifying genetic locus assignment of HLA-DRB genes

Immunology Today, 1994
The DR haplotypes of the human major histocompatibility complex have been arranged in five haplotypic groups based on genomic cloning and sequence analyses. To date, the expressed DRB sequences have been assigned to four different loci: DRB1, 3, 4 and 5.
G, Andersson, L, Andersson, D, Larhammar, L, Rask, S, Sigurdardóttir   +4 more
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RANDOM GENETIC DRIFT IN MULTI-ALLELIC LOCUS

Evolution, 1955
In the theory that evolution is anl irregularly shifting state of balance, especially that of a subtle balance between the evolutionary pressures of mutation, immigration and selection as a group and random or stochastic processes which give rise to processes of trial and error (Wright, 1950), the process of random genetic drift is one of the problems ...
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Genetic linkage between erythrokeratodermia variabilis and Rh locus

Human Genetics, 1984
A genetic linkage study was performed in a large Dutch kindred with erythrokeratodermia variabilis (EKV, McKusick no. 13320). The autosomal-dominant trait appeared to segregate rather consistently with the cde (r) gene complex of the Rh system. Only one recombinant was found amongst 27 informative individuals.
J G, van der Schroeff, L E, Nijenhuis, P, Meera Khan, L F, Bernini, G M, Schreuder, E, van Loghem, W S, Volkers, L N, Went   +7 more
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Genetic locus heterogeneity in Lafora's progressive myoclonus epilepsy

Annals of Neurology, 1999
In 1995, we mapped a gene for Lafora's progressive myoclonus epilepsy in chromosome 6q23-25. In 1997 and 1998, we reduced the size of the locus to 300 kb, and an international collaboration identified mutations in the protein tyrosine phosphatase gene.
B A, Minassian, J, Sainz, J M, Serratosa, M, Gee, L M, Sakamoto, S, Bohlega, G, Geoffroy, C, Barr, S W, Scherer, U, Tomiyasu, S, Carpenter, K, Wigg, A V, Sanghvi, A V, Delgado-Escueta   +13 more
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Genetics of the relB locus in Escherichia coli

Journal of Bacteriology, 1977
A mutant of Escherichia coli with a delayed relaxed phenotype very similar to that of a previously described relB mutant has been obtained using a new selection procedure. The mutation giving rise to this phenotype has been shown to map at 34.5 min and to be 12% cotransducible with man. It is recessive, revertible, and most likely an allele of the relB
B, Diderichsen, N P, Fiil, R, Lavallé
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Identical genetic locus for Baltic and Mediterranean myoclonus

The Lancet, 1992
Genetic linkage analysis shows that Baltic and Mediterranean myoclonus, two forms of progressive myoclonus epilepsy, are closely linked to marker D21S113 on the long arm of chromosome 21. Baltic and Mediterranean myoclonus are most probably due to mutations of the same gene.
A, Malafosse, A E, Lehesjoki, P, Genton, P, Labauge, G, Durand, C A, Tassinari, C, Dravet, R, Michelucci, A, de la Chapelle   +8 more
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Somatic and germline genetics at the JAK2 locus

Nature Genetics, 2009
Myeloproliferative neoplasms are hematological malignancies frequently associated with somatically acquired mutation of the JAK2 gene. A new study shows that these mutations are preferentially found within a particular inherited JAK2 haplotype, implying the existence of a strong, but uncharacterized, interaction between somatic and germline genetics at
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